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Primary versus secondary recurrent pregnancy losses: Clinical findings and live birth rate after comprehensive work-up and personalized management.
Acta Obstet Gynecol Scand
January 2025
Department of Biomedical Sciences, Humanitas University, Milan, Italy.
Introduction: Recurrent pregnancy loss (RPL), defined as two or more consecutive pregnancy losses before 24 weeks of gestation, affects up to 1%-2% of couples. Aim of this retrospective cohort study was to report the main causes and pregnancy outcomes of a cohort of women with RPL and the efficacy of a personalized work-up and treatment in terms of live birth rate.
Material And Methods: Women with primary (pRPL) and secondary (sRPL) RPL underwent a complete work-up and personalized therapeutic management.
Risk Factors for Progressive Disease After Immune Checkpoint Inhibitor Therapy in Head and Neck Squamous Cell Carcinoma.
Head Neck
January 2025
Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Background: This study analyzed the clinical features of patients with recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC), who developed progressive disease (PD) after immune checkpoint inhibitor (ICI) therapy.
Methods: We retrospectively analyzed 256 patients with R/M HNSCC treated with ICIs at 11 medical centers. Associations between the treatment outcomes-best response, overall survival, and progression-free survival-and various clinical factors were analyzed.
Coblation Versus Radiofrequency for Tongue Base Reduction in Obstructive Sleep Apnea: A Meta-analysis.
OTO Open
January 2025
Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Division of Sleep Surgery Stanford University Stanford California USA.
Objective: The objective of this study is to determine the effectiveness and safety profile of coblation tongue base reduction (CBTR) compared to radiofrequency base of tongue (RFBOT) reduction on sleep-related outcomes in patients with obstructive sleep apnea (OSA).
Data Sources: PubMed, Scopus, Web of Science, and Cochrane Database of Systematic Reviews databases.
Review Methods: Literature search by 2 independent authors was conducted using the abovementioned databases.
Management of radiotherapy-induced hyposalivation using photobiomodulation therapy: a case series.
Lasers Med Sci
January 2025
Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
It is not uncommon for individuals receiving radiotherapy for head and cancers to experience dry mouth sensation (xerostomia), salivary hypofunction (hyposalivation) and taste changes. The present study aimed to evaluate the short-term effectiveness of biweekly photobiomodulation therapy (PBMT) in managing these radiotherapy-induced adverse effects and its impact on oral health-related quality of life. Ten patients who developed xerostomia and hyposalivation secondary to radiotherapy for head and neck cancer were included.
View Article and Find Full Text PDFPostural crisis in patients undergoing canalith repositioning procedures for posterior canal benign paroxysmal positional vertigo: A systematic review and meta-analysis.
Medicine (Baltimore)
January 2025
Department of Otorhinolaryngology-Head & Neck Surgery, Daegu Catholic University Medical Center, Daegu, Korea.
Background: The Epley or Semont maneuver is performed for posterior canal benign paroxysmal positional vertigo (PC-BPPV). The postural crisis indicates the phenomenon that the patient experiences severe dizziness, is unable to maintain the sitting posture, and suddenly falls backward or sideways on the examination table when returning to the sitting position, which is the final step of the canalith repositioning procedure (CRP). The postural crisis increases the risk of falls during CRP.
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