The effect of niphangin (calcium antagonist) on the hemodynamics, gaseous exchange and course of the disease was studied in 65 patients with chronic obstructive bronchitis complicated by cor pulmonale. Synchronous registration of ECG, PCG, tetrapolar rheography, phlebography. It was found that niphangin used in the complex treatment of cor pulmonale allowed to improve the gaseous exchange, central and peripheral hemodynamics and effected favourably the course of the disease.

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