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Impact of Climate Change-Induced Flooding Water Related Diseases and Malnutrition in Borno State, Nigeria: A Public Health Crisis.
Environ Health Insights
March 2025
Department of Biochemistry, Nutrition and Health Promotion, Mississippi State University, Mississippi State, MS, USA.
Climate change-induced flooding has caused public health crises in Borno State, Nigeria, which influence the increase of waterborne diseases and malnutrition. Flooding disrupts water and sanitation systems, creating breeding grounds for waterborne diseases such as cholera, malaria, and diarrheal illnesses. The displacement of communities and destruction of agricultural infrastructure due to flooding further increase food insecurity, leading to malnutrition.
View Article and Find Full Text PDFCharacterization of Vibrio cholerae from the Jukskei River in Johannesburg South Africa.
Lett Appl Microbiol
March 2025
Department of Clinical Microbiology and Infectious Diseases, Faculty of Health Science, University of Witwatersrand, 7 York Road, Parktown, Johannesburg, South Africa.
The current study aimed to isolate and characterize Vibrio cholerae (V. cholerae) isolated from the Jukskei River, one of the largest Rivers in Johannesburg, South Africa. Water samples collected from the Jukskei River were subjected to culture-based methods for the detection and isolation of V.
View Article and Find Full Text PDFA Demographic Study of Aste-Béon (Ossau Valley, Bearn), a Small Community From French Western Pyrenees in the 19th Century.
Am J Hum Biol
March 2025
Laboratoire PACEA UMR CNRS 5199, Université de Bordeaux, Pessac, France.
Objectives: To decipher the social behaviors and public health status of a 19th-century small Western Pyrenean community using various historical demography data.
Methods: From censuses, civil and parish registers of births, marriages, and deaths/burials, migration archives, and administrative records, we analyzed a series of demographic parameters in the village of Aste-Béon between 1801 and 1900.
Results: Acknowledging the limitations of such a historical demography approach (especially losses of data and underreporting of deaths of very young individuals), this study enabled us to draw a series of conclusions.
Discovery of mono-ADP ribosylating toxins with high structural homology to Pseudomonas exotoxin A.
Commun Biol
March 2025
Department of Life Sciences, University of Bath, Bath, UK.
Mono-ADP-ribosyl transferase (mART) proteins are secreted virulence factors produced by several human pathogens, the founding member being diphtheria toxin (DT). Pseudomonas aeruginosa can also secrete a mART toxin, known as exotoxin A (PE), but with an organization of its three functional domains (receptor, translocation, and enzymatic elements) that is opposite to DT. Two additional PE-like toxins (PLTs) have been identified from Vibrio cholerae and Aeromonas hydrophila, suggesting more PLT family members may exist.
View Article and Find Full Text PDFCholera is a diarrheal disease that continues to burden vulnerable populations globally, primarily due to lack of clean water, optimal sanitation and adequate health infrastructure. Understanding the kinetics of antibody responses elicited by toxigenic infection can inform the Sero-epidemiological estimation of disease burden and impact of vaccination efforts. While antibody kinetics have been well-described in South Asia, such studies based in Africa are lacking, despite the ongoing prevalence of cholera in that region.
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