Emergence of a unique penicillin-resistant Streptococcus pneumoniae serogroup 35 strain.

J Clin Microbiol

Department of Medicine, Marshall University, Joan C. Edwards School of Medicine, Byrd Clinical Center, 1249 15th Street, Huntington, WV 25701, USA.

Published: January 2011

AI Article Synopsis

  • Seven Streptococcus pneumoniae serogroup 35 isolates were analyzed using pulsed-field gel electrophoresis and pbp2b gene sequencing.
  • Among the isolates, three penicillin-susceptible strains and one intermediate-resistant strain showed complete genomic identity with the prototype strain R6.
  • Two resistant strains and one additional intermediate strain had unique sequences that distinguished them from the others, indicating genetic diversity.

Article Abstract

We analyzed seven Streptococcus pneumoniae serogroup 35 isolates by pulsed-field gel electrophoresis of the genome and pbp2b gene nucleotide sequences. Three penicillin-susceptible strains and one penicillin-intermediate-resistant strain exhibited 100% identity to prototype R6. Two resistant strains and one other intermediate strain differed from them and contained a unique sequence.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020440PMC
http://dx.doi.org/10.1128/JCM.01620-10DOI Listing

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