Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The role of metabolites in the progression of osteoarthritis: Mechanisms and advances in therapy.
J Orthop Translat
January 2025
Department of Orthopaedics, Shanghai Sixth People's Hospital Fujian, No. 16, Luoshan Section, Jinguang Road, Luoshan Street, Jinjiang City, Quanzhou, Fujian, China.
Unlabelled: Osteoarthritis (OA) is a progressive degenerative disease affected by many factors, and there is currently no effective treatment. In recent years, the latest progress in metabolomics in OA research has revealed several metabolic pathways and new specific metabolites involved in OA. Metabolites play significant roles in the identification and management of OA.
View Article and Find Full Text PDFRecent Advances in the Design and Application of Asymmetric Carbon-Based Materials.
Small Methods
January 2025
College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang, 050018, P. R. China.
Asymmetric carbon-based materials (ACBMs) have received significant attention in scientific research due to their unique structures and properties. Through the introduction of heterogeneous atoms and the construction of asymmetric ordered/disordered structures, ACBMs are optimized in terms of electrical conductivity, pore structure, and chemical composition and exhibit multiple properties such as hydrophilicity, hydrophobicity, optical characteristics, and magnetic behavior. Here, the recent research progress of ACBMs is reviewed, focusing on the potential of these materials for electrochemical, catalysis, and biomedical applications and their unique advantages over conventional symmetric carbon-based materials.
View Article and Find Full Text PDFReal-world treatment patterns and health outcomes for patients with myelofibrosis treated with fedratinib.
Future Oncol
January 2025
Bristol Myers Squibb, Princeton, NJ, USA.
Aim: Assess real-world fedratinib (FEDR) treatment patterns and clinical outcomes in patients with primary or secondary myelofibrosis following discontinuation of ruxolitinib (RUX).
Patients & Methods: This study was a retrospective, noninterventional medical record review of patients in Canada, Germany, and the United Kingdom (UK). A total of 70 physicians (primarily hematologist-oncologists [78.
Unraveling the dual role of bilirubin in neurological Diseases: A Comprehensive exploration of its neuroprotective and neurotoxic effects.
Brain Res
January 2025
Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga 142001, Punjab, India. Electronic address:
Neurodegenerative disorders are characterized by a progressive loss of neurons, causing substantial deficits in motor and cognitive functioning. Bilirubin is a yellow by-product of heme, existing in two primary isoforms namely unconjugated and conjugated, while initially produced unconjugated isomer is lipophilic and cytotoxic in nature. At physiological levels, bilirubin has an important role in brain function by acting as a powerful antioxidant, preventing brain tissues from oxidative damage by eliminating reactive oxygen species (ROS).
View Article and Find Full Text PDF[The pathology of pediatric in China over the past ten years: retrospect and prospect].
Zhonghua Bing Li Xue Za Zhi
February 2025
Department of Pathology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
In the past decade, governments, including the national, provincial, municipal, and others, have increased their investment in children's health. Pathologists, especially pediatric pathologists, have greatly promoted the development and progress of pediatric pathology in China with the guidance of molecular pathological technology. This article reviews the cultivation of pediatric pathology talents, the application of new technologies, clinical pathological diagnosis and research, as well as many other aspects over the past decade, and looks forward to the future development of pediatric pathology.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!