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Nerve Ultrasound Detects Nerve Atrophy in Patients With Ataxia-Telangiectasia: A Pilot Study.
Muscle Nerve
March 2025
Division of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Ceará, Brazil.
Introduction/aims: Ataxia-telangiectasia (A-T) is a genetic multisystem neurodegenerative disorder characterized by cerebellar ataxia, oculocutaneous telangiectasia, extrapyramidal involvement, peripheral sensorimotor neuropathy, immunodeficiency, pulmonary disease, and an increased risk of malignancy that ultimately determines the shortened lifespan in many patients. A-T nerve ultrasonographic characteristics remain underexplored. This pilot study aimed to characterize the ultrasonographic morphology of peripheral nerves in patients with A-T.
View Article and Find Full Text PDFEffect of three traditional conservative treatment techniques on patients with mild-to-moderate carpal tunnel syndrome: A systematic review and meta-analysis.
J Hand Ther
March 2025
College of Physical Education, Anqing Normal University, Anqing, China.
Background: Carpal tunnel syndrome (CTS) is a common peripheral nerve entrapment syndrome that can be treated in a variety of ways, including manual therapy, massage, and acupuncture.
Purpose: Traditional conservative treatment techniques have been widespread used for treatment of patients with mild-to-moderate carpal tunnel syndrome (CTS), such as manual therapy, massage, and acupuncture. However, there appears to be no consensus about the benefits of traditional conservative treatment techniques for patients with CTS.
Immersive virtual contexts, engagement, and emotions: How do these factors influence sensory acceptance?
Food Res Int
April 2025
Department of Food Technology, Federal University of Viçosa, Peter Henry Rolfs Avenue, 36570-900 Viçosa, MG, Brazil. Electronic address:
Although virtual reality (VR) holds great potential in sensory research, further investigations are needed to assess the impact of immersion on consumer evaluations. Previous studies have limitations, such as a small number of evaluators, inconsistent graphical quality of virtual environments, lack of comparisons with traditional laboratory settings, and insufficient data on consumer engagement during virtual assessments. To address these gaps, this study evaluated consumer engagement using a presence scale, along with acceptance and emotions evoked during the consumption of an industrial beer (American Lager).
View Article and Find Full Text PDFUnderstanding human amygdala function with artificial neural networks.
J Neurosci
March 2025
Emory University, Atlanta, GA 30032
The amygdala is a cluster of subcortical nuclei that receives diverse sensory inputs and projects to the cortex, midbrain, and other subcortical structures. Numerous accounts of amygdalar contributions to social and emotional behavior have been offered, yet an overarching description of amygdala function remains elusive. Here we adopt a computationally explicit framework that aims to develop a model of amygdala function based on the types of sensory inputs it receives, rather than individual constructs such as threat, arousal, or valence.
View Article and Find Full Text PDFThe protective effect of Fingolimod upon visual behavior in a demyelination animal model is associated with synaptopathy prevention.
Neurotoxicology
March 2025
Laboratório de Biologia Celular e Tecidual, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Brasil. Electronic address:
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS that causes motor, cognitive, and sensory dysfunctions, with visual disorder being one of the most prevalent. Synaptopathy has been recognized as one of the predominant pathogenic components of MS. We previous characterized inhibition of synaptopathy in the visual thalamus using the cuprizone-induced demyelination MS animal model.
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