Ned Tijdschr Geneeskd
Medisch Centrum Haaglanden, Afd. Gynaecologie, Den Haag, the Netherlands.
Published: November 2010
A previously healthy 33-year-old woman presented at 13 weeks gestation in a comatose state after a new onset of seizures. Evaluation revealed an intraventricular haemorrhage from an arterioventricular malformation. Coma in pregnancy is a rare event. The moral, legal and medical aspects of prolongation of pregnancy, termination, withdrawal of medical treatment and organ donation are discussed.
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Lancet Neurol
March 2025
Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. Electronic address:
Background: There is an unmet need for high-quality data from prospective studies on the safety and effectiveness of direct oral anticoagulants (DOACs) for the treatment of cerebral venous thrombosis (CVT). We aimed to compare the safety and effectiveness of DOACs versus vitamin K antagonists (VKAs) for the treatment of CVT in a setting that reflects daily clinical practice.
Methods: DOAC-CVT was an international, prospective, observational cohort study done in 65 hospitals in 23 countries across five continents.
JAMA Netw Open
February 2025
Department of Rehabilitation Medicine, NYU Grossman School of Medicine, New York, New York.
Importance: General trauma is the leading cause of nonobstetric maternal morbidity and mortality, affecting approximately 8% of all pregnancies. Pregnant women with traumatic brain injury (TBI) face high morbidity and mortality rates, requiring complex management due to physiological changes, teratogenic risks of treatments, and the need for fetal monitoring.
Objectives: To assess the consequences of TBI during pregnancy on maternal and fetal outcomes and to evaluate management strategies to inform clinical decision-making.
Transplant Proc
February 2025
Department of Surgery, Tulane University, New Orleans, Louisiana. Electronic address:
Background: Organ procurement from brain-dead pregnant women is rare and typically occurs postfetal delivery. In this case report, we describe organ procurement from a brain-dead woman in her third trimester of pregnancy with a nonviable fetus remaining in utero.
Case Summary: We report a 33-year-old woman at 38 weeks gestation who suffered anoxic brain injury following cardiac arrest due to suspected opioid overdose.
Cureus
November 2024
Neurology, Park Hospital, Gurgaon, IND.
We report a primigravida 31-year-old female patient hospitalized at 32 gestational weeks with status epilepticus. In due course of illness, she developed refractory status epilepticus managed with induced coma with propofol and emergency early lower section caesarean surgery (LSCS). A battery of initial laboratory and radiological tests did not lead to a definite diagnosis.
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