Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer.

Cancer Immunol Immunother

H. Lee Moffitt Cancer Center, MRC 2067, 12902 Magnolia Dr, Tampa, FL 33612, USA.

Published: March 2011

In recent years, the combination of cancer immunotherapy with standard therapeutic modality is gaining credibility due to a number of clinical trials demonstrating therapeutic success of such combination therapies. However, the mechanism of this phenomenon is poorly understood. Here, we will discuss recent findings that suggest novel mechanisms of synergistic effect of cancer immunotherapy and chemotherapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11029574PMC
http://dx.doi.org/10.1007/s00262-010-0930-1DOI Listing

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