Menstrual complaints are common and include pain, abnormal bleeding, and menstrual irregularity. The etiology is wide-ranging and includes endometriosis, fibroids, adenomyosis, pelvic congestion syndrome, pelvic inflammatory disease, endometrial hyperplasia, and polyps. Polycystic ovarian syndrome and some congenital uterine anomalies may present with menstrual disturbance and have been included in this review. Transvaginal ultrasound is widely used as first-line investigation. Magnetic resonance imaging is used increasingly with high diagnostic accuracy and confidence. Its multiplanar capacity and superior tissue contrast resolution enable accurate presurgical mapping of fibroids, deep pelvic endometriosis, and adenomyosis. Similarly, accurate differentiation of congenital uterine anomalies depends on multiplanar imaging with either 3-dimensional ultrasound or magnetic resonance imaging. Recent advances in imaging and radiological intervention, combined with an understanding of the underlying causes of menstrual dysfunction, therefore aid in accurate diagnosis and optimal treatment planning.
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http://dx.doi.org/10.1053/j.sult.2010.08.001 | DOI Listing |
Am J Case Rep
March 2025
Faculty of Medicine, University of Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
BACKGROUND The prevalence of female genital tract anomalies is around 4-6.9%. Vaginal agenesis is a form of Müllerian agenesis and defined as the congenital absence of the vagina.
View Article and Find Full Text PDFTaiwan J Obstet Gynecol
March 2025
Fundación Cardiovascular de Colombia, Piedecuesta, Santander, Colombia.
Objective: Describe a clinical case of a patient with Herlyn Werner Wunderlich Syndrome in whom an accurate diagnosis was not made during menarche due to failures in her care and poor diagnostic suspicion.
Case Report: Female patient, 21 years old, without medical history, menarche at 12 years of age, with hypermenorrhea and recurrent urinary tract infection. Patient with uterus-dependent mass associated with left renal agenesis, laparotomy was performed with the finding of a didelphic uterus and compensatory hypertrophy of the right kidney, uterine growth with widening of the endometrial cavity and right adnexal septated cyst, absence of left kidney, bicornuate uterus, bicollis, distended vagina and hematocolpos with these findings, clinical genetics considers Herlyn Werner Wunderlich Syndrome.
Int J Gynaecol Obstet
March 2025
University College Hospital Galway, University of Galway, Galway, Ireland.
Both chemotherapy and radiotherapy can cause infertility in a patient undergoing cancer therapy. As both the ovaries and uterus are involved in female patients, the effects are profound. Where cryopreservation is not used or is unavailable, reproductive options include spontaneous conception if fertility returns, donor gametes, adoption, and surrogacy.
View Article and Find Full Text PDFHistol Histopathol
February 2025
Department of Surgical Pathology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan.
, the gene responsible for Fukuyama congenital muscular dystrophy (FCMD), is involved in the glycosylation of α-dystroglycan (α-DG). On the other hand, fukutin is expressed in various organs, and the roles of fukutin in non-neuromuscular tissues are not fully elucidated. In the present immunohistochemical study of uterine cervical carcinoma, Ki-67-positive cells tended to be more in areas showing weaker expression of fukutin.
View Article and Find Full Text PDFPlacenta
February 2025
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan.
Objective: Marginal cord insertion (MCI) is often defined as an abnormal placental cord insertion (PCI), yet there is limited discussion on the maternal backgrounds and perinatal complications associated with its occurrence. This retrospective cohort study aimed to investigate maternal backgrounds associated with MCI and to compare perinatal outcomes between MCI and normal PCI.
Materials And Methods: The study included 1038 deliveries from 2021 to 2023 in our institution, examining maternal backgrounds and perinatal outcomes.
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