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The elderly population is increasing worldwide. Despite a major decrease in deaths from coronary heart disease (CHD), this malady remains the major cause of death in elderly men and women. In this paper, we review the role of dyslipidemia as a major known risk factor in the pathogenesis of CHD, age-related changes in lipoprotein metabolism, and differences in changes in lipids that occur in men and women during aging. Next we provide an overview of the available studies and recommendations from ATP III. Finally, we comment on the screening and management, cost and side effects of therapy as it applies to an aging population.
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http://dx.doi.org/10.1177/1753944710385048 | DOI Listing |
Psychophysiology
March 2025
ARCHA, HLS, School of Psychology, Aston University, Birmingham, UK.
With an aging global population, the number of older adults with age-related changes in the brain, including dementia, will continue to increase unless we can make progress in the early detection and treatment of such conditions. There is extensive literature on the effects of aging on the EEG, particularly a decline in the Peak Alpha Frequency (PAF), but here, in a reversal of convention, we used the EEG power-frequency spectrum to estimate chronological age. The motivation for this approach was that an individual's brain age might act as a proxy for their general brain functioning, whereby a discrepancy between chronological age and EEG age could prove clinically informative by implicating deleterious conditions.
View Article and Find Full Text PDFInt J Geriatr Psychiatry
March 2025
Psychosomatic Medical Center, The Fourth People's Hospital of Chengdu, Chengdu, China.
Objectives: In China, depressive disorder (DD) among middle-aged and older adults is a significant public health concern. This research utilized the latest Global Burden of Disease Study (GBD) database to evaluate the evolving disease burden of DD in this demographic over the past 3 decades.
Methods: Data on the incidence and disability-adjusted life years (DALY) of DD among people aged 45-89 in China between 1992 and 2021 were collected from the GBD 2021.
Drug Alcohol Rev
March 2025
Santé Publique France, Saint-Maurice, France.
Introduction: The increasing heavy and sustained use of nitrous oxide (NO) for recreational purposes in several countries is a growing public health issue, as it can cause neuropathy and other harms. Documenting recreational NO use prevalence and characteristics of people who use the drug in the general population is essential.
Methods: Between 2 March and 9 July 2022, we conducted a nationwide survey of a random sample of adults in France to estimate the prevalence of NO awareness and reported use.
Ind Health
March 2025
School of Commerce, Waseda University, Japan.
Few studies have addressed the relationship between sleep and employment in Japan. We use four waves of the Japan Study of Aging and Retirement (JSTAR) to address the relationship between weekday sleep duration, self-reported sleep quality and four self-reported indicators of sleep quality and employment status (model 1, full sample), working hours and job satisfaction (model 2, working sample) among individuals aged 50 and over (N=7,082). We apply mixed effects models for the linear outcome of sleep duration and cumulative link mixed models for the sleep quality variables, controlling for socio-demographic and health characteristics.
View Article and Find Full Text PDFPediatr Obes
March 2025
Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
Objectives: This study examined the impact of hypothetical interventions on (i) early life factors (prenatal and early postnatal) on rapid weight gain during infancy, and (ii) early life factors and child energy balance-related behaviours (EBRB) on children's body mass index (BMI)-for-age at 5 and 8 years.
Methods: Data from the Norwegian Mother, Father, and Child Cohort Study included participants aged 2 (n = 48 109), 5 (n = 18 810) and 8 (n = 10 830) years. Early life intervention variables were maternal smoking during pregnancy, maternal weight before and during pregnancy, exclusive/partial breastfeeding for 6 months, and introduction of complementary food at 6 months.
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