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Causal Relationship Between Different Sleep Traits and Dental Caries: A Bidirectional Mendelian Randomization Study.
Int J Behav Med
January 2025
Department of Stomatology, Zhejiang Hospital, Hangzhou, China.
Background: Dental caries (DC) is a significant common disease of the oral cavity. Recently, researchers have focused more on the impact of poor sleep habits on the incidence and development of DC, which aroused our interest in the study of the correlation and causal relationship between sleep and dental caries.
Methods: In this study, Linkage disequilibrium score (LDSC) regression method was used to found the genetic correlation between different sleep traits and DC, while bidirectional Mendelian randomization (MR) methods were used to explore the causal relationship.
Descriptive study on oral health and pathologies in vulnerable migrant adolescents from North and West Africa.
Sci Rep
January 2025
Department of Dentistry, Faculty of Health Sciences, Universidad Fernando Pessoa Canarias, Santa María de Guía, Gran Canaria, Spain.
This descriptive study focuses on the oral health of African migrants, especially adolescents, arriving in the Canary Islands. Notably, these patients show a high prevalence of caries and oral mucosal alterations. These are influenced by multifactorial factors, such as living conditions in their country of origin, hygiene habits, and sugar-rich diets.
View Article and Find Full Text PDFIntroduction: This study examined the association between cardiovascular disease (CVD) history and their dental caries experience status.
Methods: Conducted from January 2021 to June 2023, this cross-sectional cohort study involved 7,138 participants who underwent oral examinations. Data on demographic background, oral health-related behaviors, and smoking status were collected using a structured questionnaire.
An introduction to antibacterial materials in composite restorations.
JADA Found Sci
October 2024
Division of Biomaterial and Biomedical Sciences, Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, OR.
The longevity of direct esthetic restorations is severely compromised because of, among other things, a loss of function that comes from their susceptibility to biofilm-mediated secondary caries, with being the most prevalent associated pathogen. Strategies to combat biofilms range from dental compounds that can disrupt multispecies biofilms in the oral cavity to approaches that specifically target caries-causing bacteria such as . One strategy is to include those antibacterial compounds directly in the material so they can be available long-term in the oral cavity and localized at the margin of the restorations, in which many of the failures initiate.
View Article and Find Full Text PDFInflammation is a complex host response to harmful infections or injuries, playing both beneficial and detrimental roles in tissue regeneration. Notably, clinical dentinogenesis associated with caries development occurs within an inflammatory environment. Reparative dentinogenesis is closely linked to intense inflammation, which triggers the recruitment and differentiation of dental pulp stem cells (DPSCs) into the dentin lineage.
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