Early treatment of meningococcal meningitis is mandatory but may negate the cerebrospinal fluid culture. Etiological diagnosis then mainly relies on PCR. Here, we report a case of false-negative results for real-time PCR for a Neisseria meningitidis serogroup B isolate with a polymorphism in the ctrA gene.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008480PMC
http://dx.doi.org/10.1128/JCM.01766-10DOI Listing

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