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Ranking Magnetic Colloid Performance for Magnetic Particle Imaging and Magnetic Particle Hyperthermia.
Adv Funct Mater
January 2025
Magnetic particle imaging (MPI) is an emerging modality that can address longstanding technological challenges encountered with magnetic particle hyperthermia (MPH) cancer therapy. MPI is a tracer technology compatible with MPH for which magnetic nanoparticles (MNPs) provide signal for MPI and heat for MPH. Identifying whether a specific MNP formulation is suitable for both modalities is essential for clinical implementation.
View Article and Find Full Text PDFSmart Directional Liquid Manipulation on Curvature-Ratchet Surfaces.
ACS Nano
January 2025
Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China.
Structured surfaces leverage interfacial energy for directional liquid manipulation without external power, showing tremendous potential in microfluidics, green energy and biomedical applications. While the interplay of interfacial energy between solid surfaces and liquids is crucial for liquid manipulation, a systematic understanding of how the balance in liquid-solid interfacial energy affects liquid behaviors remains lacking. Here, using the curvature-ratchet surface as a generic example, we reveal the complex directional liquid dynamics inherent in the subtle regulation of liquid-solid interfacial energy.
View Article and Find Full Text PDFSignal theory based encryption of faster-than-Nyquist signals for fiber and wireless transmission.
Commun Eng
January 2025
THz-Photonics Group, Technische Universität Braunschweig, Braunschweig, Germany.
New applications such as the Internet of Things, autonomous driving, Industry X.0 and many more will transmit sensitive information via fibers and over the air with envisioned data rates beyond terabits per second. Therefore, the encryption has to be simple, fast and spectrally efficient, so that the power consumption and latency are low and the scarce bandwidth is not wasted.
View Article and Find Full Text PDFSpherical harmonics texture extraction for versatile analysis of biological objects.
PLoS Comput Biol
January 2025
European Molecular Biology Laboratory, Cell Biology and Biophysics Unit, Heidelberg, Germany.
The characterization of phenotypes in cells or organisms from microscopy data largely depends on differences in the spatial distribution of image intensity. Multiple methods exist for quantifying the intensity distribution - or image texture - across objects in natural images. However, many of these texture extraction methods do not directly adapt to 3D microscopy data.
View Article and Find Full Text PDFRetroFun-RVS: A Retrospective Family-Based Framework for Rare Variant Analysis Incorporating Functional Annotations.
Genet Epidemiol
March 2025
Department of Social and Preventive Medicine, Laval University, Quebec City, Quebec, Canada.
A large proportion of genetic variations involved in complex diseases are rare and located within noncoding regions, making the interpretation of underlying biological mechanisms a daunting task. Although technical and methodological progress has been made to annotate the genome, current disease-rare-variant association tests incorporating such annotations suffer from two major limitations. First, they are generally restricted to case-control designs of unrelated individuals, which often require tens or hundreds of thousands of individuals to achieve sufficient power.
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