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[11-Hydroxycorticoid, 17-hydroxycorticoid].
Nihon Rinsho
July 2010
Department of Internal Medicine, Atami Hospital, International University of Health and Welfare.
The mineralcorticoid effects of carbenoxolone sodium are well established and seem related to the ulcer healing of the drug. In the present study the plasma 11 hydroxycorticoid responses were assessed in 12 patients undergoing treatment with carbenoxolone for chronic gastric ulceration. After treatment with carbenoxolone for one month the plasma 11 hydroxycoticoid levels rose significantly, suppression by dexamethosone was less marked and the normal diurnal periodicity was abolished.
View Article and Find Full Text PDFMorning plasma 11-hydroxycorticoids, urinary 11-hydroxycorticoids, and urinary 17-oxogenic steroids were measured before and during a dexamethasone suppression test. This consisted in the administration by mouth of 2 mg of dexamethasone daily for 48 hours, followed by 8 mg daily for 48 hours. In addition midnight plasma 11-hydroxycorticoids were measured before the start of the test.
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