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This study aimed to develop novel hydrogels using polycaprolactone (PCL), nano-silver (Ag), and linalool (Lin) to address the challenge of increasing antimicrobial resistance in healing infected wounds. The hydrogels' morphological properties, in vitro release profiles, antibacterial efficacy, and safety were investigated. Hydrogels were prepared from PCL/Ag, PCL/Lin, and PCL/Ag/Lin formulations and applied to infected wounds.
View Article and Find Full Text PDFMultifunctional Biological Performance of Electrospun PCL Scaffolds Formulated with Silver Sulfide Nanoparticles.
Polymers (Basel)
January 2025
Centro de Investigación y Desarrollo Tecnológico en Electroquímica SC, Parque Tecnológico Querétaro s/n Sanfandila, Pedro Escobedo, Querétaro 76703, Mexico.
Our work describes the green synthesis of silver sulfide nanoparticles (AgS NPs) and their formulation into polycaprolactone fibers (PCL), aiming to improve the multifunctional biological performance of PCL membranes as scaffolds. For this purpose, an extract of rosemary () was employed as a reducing agent for the AgS NPs, obtaining irregular NPs and clusters of 5-60 nm, with a characteristic SPR absorption at 369 nm. AgS was successfully incorporated into PCL fibers by electrospinning using heparin (HEP) as a stabilizer/biocompatibility agent, obtaining nanostructured fibers with a ca.
View Article and Find Full Text PDFGenomic and mutational analysis of Pseudomonas syringae pv. tagetis EB037 pathogenicity on sunflower.
BMC Microbiol
January 2025
USDA-ARS, Sustainable Agricultural Systems Laboratory, Beltsville Agricultural Research Center, Beltsville, MD, 20705, USA.
Background: Pseudomonas syringae pv. tagetis (Pstag) causes apical chlorosis on sunflower and various other plants of the Asteraceae family. Whole genome sequencing of Pstag strain EB037 and transposon-mutant derivatives, no longer capable of causing apical chlorosis, was conducted to improve understanding of the molecular basis of disease caused by this pathogen.
View Article and Find Full Text PDFDifferences in influenza testing and treatment in micropolitan versus metropolitan areas in the U.S. using medicare claims data from 2010 to 2016.
BMC Public Health
January 2025
Epidemiology and Prevention Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS 24/7, Atlanta, GA, 30329-4027, USA.
Background: To improve understanding of influenza and rurality, we investigated differences in influenza testing and anti-viral treatment rates between micropolitan (muSAs) and metropolitan statistical areas (MSAs) using national medical claims data over multiple influenza seasons.
Methods: Using billing data from the Centers for Medicare and Medicaid Services for those aged 65 years and older, we estimated weekly rates of ordered rapid influenza diagnostic tests (RIDT) and antivirals (AV) among Medicare enrollees by core-based statistical areas (CBSAs) during 2010-2016. We used Negative Binomial generalized mixed models to estimate adjusted rate ratios (aRR) between MSAs and muSAs, adjusting for clustering by CBSA plus explanatory variables.
Atomically precise silver-based bimetallic clusters for electrocatalytic urea synthesis.
Natl Sci Rev
February 2025
Henan Key Laboratory of Crystalline Molecular Functional Materials, College of Chemistry, Zhengzhou University, Zhengzhou 450001, China.
Electrocatalytic urea synthesis from CO and nitrate holds immense promise as a sustainable strategy, but its complicated synthesis steps and controversial C-N coupling mechanism restrict the design of efficient catalysts. Atomically precise metal cluster materials are ideal model catalysts for investigating the C-N coupling issues. Here we synthesize two atomically precise bimetallic clusters, AgPd(PTFE)(TPP) and AgAu(PTFE)(DPPP), both with icosahedral cores and similar ligands.
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