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A previously healthy female infant was brought to the paediatrics outpatient department by her mother reporting increased irritability and swelling behind her left shoulder, accompanied by restricted movement in her left arm. The irritability had been present for the past 5 months, with swelling also noticed at that time, gradually increasing in size. On examination, a large, firm, immobile mass was detected on the left scapular region.

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A 78-year-old woman with a history of breast cancer, melanoma, and radiation therapy presented with worsening chronic osteomyelitis and radiation necrosis of her clavicle, scapula, and upper ribs. Despite treatment with vancomycin, she experienced significant lymphedema and near-total loss of motor function in the left upper extremity. Given the progression of the disease and diminished functionality of the limb, a forequarter amputation was determined to be the only viable option beyond supportive care.

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Article Synopsis
  • Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disease primarily found in children and adolescents, and sacroiliitis is an inflammatory condition of the sacroiliac joint diagnosed via MRI.
  • A case study details a 17.5-year-old female patient with classical Ehlers-Danlos syndrome (EDS) who experienced joint pain, hypermobility, and morning stiffness, leading to the diagnosis of CNO and sacroiliitis after a whole-body MRI revealed inflammation.
  • The patient was successfully treated with a combination of medications including risedronate sodium and methotrexate, achieving remission, highlighting the importance of interdisciplinary cooperation for managing the overlapping conditions.
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Introduction And Importance: Acute scapular osteomyelitis is an exceptional entity with a misleading clinical presentation. If not urgently diagnosed and treated correctly, it may lead to articular surfaces damage, deformation of the humeral head, and humerus shortening.

Case Presentation: A 12-year-old boy without any medical history with osteomyelitis of the scapular neck complicated with secondary septic arthritis of the gleno-humeral joint was evaluated.

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