AI Article Synopsis
- Acute phase proteins (APP), like C-reactive protein (CRP) and haptoglobin (Hp), serve as indicators of inflammation and disease in pigs, making them potential markers for assessing pig health and welfare.
- Reference ranges for baseline APP concentrations are essential for their use in herd health management; the study established specific ranges for CRP, Hp, Pig-MAP, and transthyretin (TTR) in boars from a high health commercial herd.
- Significant differences in APP concentrations were identified across seven commercial breeding lines, and correlations between various APPs were also observed.
Article Abstract
Acute phase proteins (APP) are used as markers of inflammation and sub-clinical disease and are considered potential biomarkers for pig health and welfare. However, reference ranges for their baseline concentrations are necessary before their use can be considered in routine herd health. In this study, C-reactive protein (CRP), haptoglobin (Hp), pig-major acute-phase protein (Pig-MAP) and transthyretin (TTR) baseline concentrations were determined in boars from a high health commercial herd and differences between seven commercial breeding lines within the herd were investigated. Reference ranges of 3.6-183 mg/L for CRP, 0.01-1.31 g/L for Hp, 0.32-2.9 g/L for Pig-MAP and 174-610 mg/L for TTR were found. Correlations were determined between Hp and CRP, Hp and Pig-MAP and CRP and Pig-MAP. Additionally, significant differences were found among the concentrations of CRP, Pig-MAP and TTR in seven commercial breeding lines.
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| http://dx.doi.org/10.1016/j.vetimm.2010.09.003 | DOI Listing |
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