Placenta: chronicle of intrauterine growth restriction.

F1000 Med Rep

Division of Maternal-Fetal Medicine and Ultrasound, Depart of Obstetrics and Gynecology, Washington University School of Medicine 660 South Euclid Ave, Maternity Building, 5th Floor, St Louis, Missouri 63110 USA.

Published: September 2010

The foundation for adult health is laid in utero and requires a healthy placenta. A common manifestation of abnormal placental development is impaired fetal growth. While placental pathology is the final common denominator in many cases of fetal growth restriction, a variety of discreet lesions have been described involving both the maternal and fetal circulations at their confluence in the placenta. Detailed examination of the placenta provides a means of elucidating the pathophysiology of poor fetal growth. This is an essential step in developing effective strategies for the prediction, prevention, and possible treatment of the growth restricted fetus.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954425PMC
http://dx.doi.org/10.3410/M2-69DOI Listing

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