A 65-year-old female had psoriasiform, depigmented, angiolupoid, lupus pernio, papular and verrucous plague type of cutaneous sarcoidosis. Systemic involvement (hepatomegaly, bilateral persistent swelling of the parotid glands, pain in the hands, weakness and atrophic rhinitis of the left nasal cavity) was also present. The histopathological features of a non-caseating epithelioid cell granuloma with giant cells confirmed the diagnosis. The patient is responding favourably to prednisolone 10 mg daily.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Cutaneous Adverse Reactions of Immunotherapy in Patients with Advanced Melanoma.
Cancers (Basel)
March 2023
1st Dermatology Department, "Andreas Syggros" Hospital for Skin Diseases, National & Kapodistrian University of Athens, 16121 Athens, Greece.
Immune checkpoint blockers (ICBs) have been widely used during the last decade for the treatment of various tumors, including advanced and metastatic melanoma. While these agents have improved melanoma patients' survival rates, they have also been associated with various autoimmune toxicities, with the skin being most commonly affected. The severity of cutaneous toxicity can not only negatively affect patients' quality of life but can also limit the proper treatment of cancer.
View Article and Find Full Text PDFUnusual clinical presentations in leprosy: a case series and review.
Trans R Soc Trop Med Hyg
July 2023
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Article Synopsis
- Leprosy has traditionally been categorized into specific types, but this classification overlooks many unusual clinical forms that can complicate diagnosis.
- The study aims to showcase eight uncommon presentations of leprosy observed over a decade, highlighting rare forms such as psoriasiform plaques and Lazarine leprosy.
- The findings emphasize the importance of recognizing these atypical presentations to ensure accurate diagnosis and timely treatment, ultimately preventing severe complications from this treatable disease.
Psoriasiform syphilis: A challenge.
Dermatol Reports
November 2021
Dermatology Unit, Galliera Hospital, Genoa, Italy.
Syphilis is one of the greatest masqueraders in dermatology, like mycosis fungoides or sarcoidosis. In fact, secondary syphilis can simulate different dermatological conditions, not only clinically but also histopathologically. A 34-year-old Brazilian man from Manaus (Amazonas) attended our Department complaining for 2 weeks of asthenia, weight loss and multiple asymptomatic disseminated erythematous papules and scaly plaques with well-defined borders and a tendency to confluence were observed on the trunk, neck and extremities, clinically similar to psoriasis guttata.
View Article and Find Full Text PDFSystemic Sarcoidosis with Psoriasiform Plaques and Patchy Nonscarring Alopecia.
Adv Skin Wound Care
August 2021
In the Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Eqypt, Shaimaa Ismail Omar, MD, is Lecturer; Rasha Mahmoud Genedy, MD, is Assistant Professor; and Sami Abdelhamid Abo Zaid, MD, is Professor. The authors have disclosed no financial relationships related to this article. Submitted September 12, 2020; accepted in revised form October 28, 2020.
Cutaneous sarcoidosis occurs in about one-quarter of patients with systemic disease and presents with either specific or nonspecific signs. Psoriasiform sarcoidosis is an uncommon presentation. Herein, study authors report a rare case of systemic sarcoidosis that presented with psoriasiform plaques and patchy alopecia.
View Article and Find Full Text PDFParadoxical eruptions to targeted therapies in dermatology: A systematic review and analysis.
J Am Acad Dermatol
May 2022
Department of Dermatology, Yale School of Medicine, New Haven. Electronic address:
Background: Antibody-based therapies that inhibit proinflammatory cytokine signaling are commonly used in dermatology. Paradoxically, these medications may induce or exacerbate inflammatory disorders.
Objective: To summarize the spectrum of manifestations, incidence, timing, potential mechanisms of, and general management approaches to paradoxical cutaneous reactions induced by cytokine-targeted antibodies in dermatology.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!