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C-H bond functionalization in the synthesis of fused 1,2,3-triazoles. | LitMetric
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C-H bond functionalization in the synthesis of fused 1,2,3-triazoles.

Jane Panteleev Karolin Geyer Angelica Aguilar-Aguilar Letian Wang Mark Lautens

Org Lett

Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, M5S 3H6, Canada.

Published: November 2010

A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide-alkyne cycloaddition and palladium-catalyzed C-H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields.

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 Source
http://dx.doi.org/10.1021/ol102342yDOI Listing

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