Severity: Warning
Message: fopen(/var/lib/php/sessions/ci_sessionl8tbs7hg3iemjf0cj4ga6kc7pb7jiqh7): Failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 177
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)
Filename: Session/Session.php
Line Number: 137
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Purpose: To describe the demographic characteristics, associated factors and causative agents of infectious keratitis in the elderly in a tertiary referral center in São Paulo, Brazil.
Methods: A retrospective review of all patients aged 60 years and over with a presumptive diagnosis of infectious keratitis who had material collected for microbiological analysis, between the years 1975 and 2007 (32-year span).
Results: From a total of 7,060 age-independent cases of microbial keratitis, 1,545 cases in the elderly were reviewed, which had a mean age of 71.0 ± 7.8 years, ranging from 60 to 101 years. There were 707 males (45.6%) and 838 females (54.3%). Associated factors were: past ocular surgery (25.1%), ocular trauma (7.2%) and contact lens use (3.0%). Bacterioscopy was positive in 40.5% of cases. Culture positivity for any agent was 53.5% (bacteria 47.0%, fungi 6.1%, Acanthamoeba 0.4%). The most frequent bacteria were the gram-positive cocci (mostly coagulase-negative Staphylococci) and gram-negative bacilli (mostly the genera Pseudomonas, Moraxella and Proteus), while the most frequent fungi were the filamentous (mostly the genus Fusarium).
Conclusions: This study represents a large series of microbial keratitis in the elderly in a single referral center. The most important factor associated with this condition in the elderly was past ocular surgery. The most frequent causative agents were bacteria, especially gram-positive cocci and gram-negative bacilli.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1590/s0004-27492010000400002 | DOI Listing |
BMC Microbiol
March 2025
Department of Parasitology, School of Medicine, China Medical University, Taichung, Taiwan.
Background: This study focuses on the detection and co-occurrence of Acanthamoeba and Klebsiella pneumoniae in freshwater river systems. Both microorganisms are known for their pathogenic potential, with Acanthamoeba capable of causing infections such as amoebic keratitis, and K. pneumoniae being a common cause of community infections.
View Article and Find Full Text PDFInt J Parasitol Drugs Drug Resist
February 2025
Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan; Department of Parasitology, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan. Electronic address:
This review examines the advancements in antimicrobial drug discovery with in vitro assays for Acanthamoeba, highlighting the efficacy of current topical antimicrobial agents. In recent decades, the treatment and diagnosis of Acanthamoeba keratitis (AK) have presented clinical challenges. Clinicians often rely on clinical judgment, risk factors, and patient travel history to guide initial treatment decisions.
View Article and Find Full Text PDFJ Nanobiotechnology
March 2025
School of Science, Shenzhen Key Laboratory of Advanced Functional Carbon Materials Research and Comprehensive Application, Harbin Institute of Technology, Shenzhen, 518055, China.
Microbial keratitis, a sight-threatening corneal infection, remains a significant global health concern. Conventional therapies using antimicrobial agents often suffers from limitations such as poor drug penetration, side effects, and occurrence of drug resistance, with poor prognosis. Novel treatment techniques, with their unique properties and targeted delivery capabilities, offers a promising solution to overcome these challenges.
View Article and Find Full Text PDFJ Ophthalmic Inflamm Infect
March 2025
Jhaveri Microbiology Centre, Hyderabad, India.
Purpose: To report the outcome of Acanthamoeba keratitis, with early addition of Photo-dynamic antimicrobial therapy with Rose Bengal (PDAT-RB) to the medical treatment (combination of 0.02% Polyhexamethylene Biguanide (PH)and 0.02% chlorhexidine(CH)).
View Article and Find Full Text PDFOcul Immunol Inflamm
March 2025
Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Purpose: To analyze the risk factors for graft failure in eyes with endothelial graft rejection following penetrating keratoplasty (PK).
Methods: Single-center, retrospective study that included patients who underwent PK at Wills Eye Hospital (2007-2018) who later presented with endothelial graft rejection, defined as clinical appearance of keratic precipitates or anterior chamber reaction. Among patients with rejection across multiple grafts, only the first PK of the first eye with documented rejection was included.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!