AI Article Synopsis
- Researchers studied how different doses of potato-derived hepatitis B virus surface antigen (P-HBsAg) could trigger immune responses in mice.
- Mice were given varying amounts of P-HBsAg, from 0.02 to 30 μg, and produced specific antibodies (IgG and IgA) regardless of the low doses used.
- A booster dose of 0.5 μg yeast-derived HBsAg (Y-HBsAg) led to enhanced antibody production in all immunized groups.
Article Abstract
The ability of potato-derived major surface antigen of hepatitis B virus (P-HBsAg) to elicit antibody responses to different dosages of P-HBsAg ranging from 0.02 to 30 μg administered orally in mice was examined. All immunized groups produced specific serum IgG and fecal IgA antibodies against P-HBsAg, even at low levels (<5 μg), after administration of a 0.5-μg yeast-derived HBsAg (Y-HBsAg; LG Life Sciences, Republic of Korea) booster.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008205 | PMC |
| http://dx.doi.org/10.1128/CVI.00262-10 | DOI Listing |
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