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The Overlooked Risk of Venous Thromboembolism in Psychiatric Patients: Epidemiology, Pathophysiology, and Implications for Clinical Care.
Semin Thromb Hemost
December 2024
Department of Hematology, Rambam Health Care Campus, Haifa, Israel.
Article Synopsis
- Psychiatric patients have a shorter life expectancy than the general population, partly due to medical, behavioral, and social factors, with venous thromboembolism (VTE) being a significant concern.
- VTE occurs more frequently in psychiatric patients—around 2 to 3 times higher than in the general population—due to factors like metabolic issues, medications, and genetic predispositions.
- Addressing the elevated risk of VTE through better risk assessment and preventive measures is crucial to improving health outcomes for these individuals.
Neutrophil/lymphocyte ratio is increased in the acute phase of schizophrenia and regardless the use and types of antipsychotic drugs.
BMC Psychiatry
December 2024
Affiliated Xiaoshan Hospital, Hangzhou Normal University, Quanfeng Zhu, 728 Yucai North Road, Hangzhou, 311201, China.
Article Synopsis
- Patients with schizophrenia experience heightened inflammation during acute episodes, and the neutrophil/lymphocyte ratio (NLR) could serve as a potential biomarker for these exacerbations.
- A study involving 651 participants (including both healthy controls and various patient groups) analyzed inflammatory indices and found that NLR was significantly higher in drug-free and medicated patients during acute phases compared to healthy individuals.
- While NLR correlated with disease duration and mood stabilizer use, the platelet/lymphocyte ratio (PLR) and monocyte/lymphocyte ratio (MLR) showed no significant differences among the patient groups or with healthy controls.
Pulmonary embolism incidence among patient admitted under psychiatry department: a case-control study.
Front Psychiatry
August 2024
Department of Psychiatry, First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Background: Pulmonary embolism (PE) is a serious and potentially life-threatening condition that requires prompt diagnosis and treatment. Identifying risk factors and diagnostic markers can aid in the early detection and management of this condition.
Methods: This case-control study examined 10,077 patients admitted to Shenzhen Kangning Hospital's psychiatry facility in 2020.
Association between antipsychotics and pulmonary embolism: a pharmacovigilance analysis.
Expert Opin Drug Saf
August 2024
Department of Pharmacy, Quanzhou Orthopedic Traumatological Hospital of Fujian University of Traditional Chinese Medicine, Quanzhou, PR China.
Background: Previous studies have documented an increased risk of pulmonary embolism (PE) in patients with schizophrenia taking antipsychotics (APs). However, specific data from real-world studies remain limited. This study aims to investigate the potential relationship between APs and PE.
View Article and Find Full Text PDF: The primary objective of this study was to compare the incidence of antipsychotic use in those with venous thromboembolism (VTE) resulting in hospital admission. This study expands upon current knowledge regarding VTE risk and antipsychotic use and investigates potential risk factors and lab values that may precede antipsychotic-induced coagulopathy. : This retrospective, case-control, chart review investigated patients admitted to an acute care hospital with either a VTE or non-VTE diagnosis.
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