Objectives: So far, there has been no practical or toxicologically non-hazardous way to decimate mites - without interrupting use of beds - in their main reservoir on bed mattresses to such an extent that the allergic condtion of people suffering from house dust mite allergies is reduced or even remedied. As so-called HygienicWood was effective against mites under simulated conditions, the influence of a mattress topper filled with HygienicWood chips on the content of mite antigen Der p1 was to be investigated and the influence on the state of health of the persons concerned analysed at the same time.

Procedure: 32 test persons suffering from dust mite allergy were randomly selected. During the course of 5 months, the influence of a HygienicWood mattress topper on the content of the mite antigen Der p1 as well as the number of bacteria, dermatophytes and yeasts in the bed dust were determined and compared with the values obtained during the 5 weeks prior to the application of HygienicWood mattress toppers. The samples were taken from between the HygienicWood mattress topper and the sheet below. At the same time, changes in well-being, state of health, typical allergy symptoms and frequency of taking antihistamines and glucocorticoids were recorded as self-assessments in the form of questionnaires.

Findings: The most striking finding was the significant decrease (p=0.000) of the house dust mite antigen Der p1 during usage of the HygienicWood mattress toppers. The effect started immediately after applying the toppers and continued with little fluctuation until the end of the observation period without lessening. At the end of the study, 43% of the test persons stated a slight improvement in their well-being. 13% of the test persons felt no change, and 6% of the test persons stated a slight deterioration. The situation was similar with regard to allergy symptoms: 43% reported a significant reduction, 38% a slight reduction, and 19% did not notice any change. The improvement in symptomatology could not be ascribed to an increased intake of antihistamines or glucocorticoids.The dermatophytes, too, showed a slight, albeit statistically not significant decrease after application of HygienicWood mattress toppers. In contrast, the pollution of bed dust with yeasts rose significantly (p=0.002), whereas there was only a tendency towards an increase in the number of bacteria, which, if one considers the slight increase, is without hygienic relevance.

Conclusion: HygienicWood mattress toppers are able to reduce the house dust mite allergen load. This leads to a distinct reduction in the allergy symptomatology, and the well-being of the persons concerned increased significantly.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951107PMC
http://dx.doi.org/10.3205/dgkh000147DOI Listing

Publication Analysis

Top Keywords

hygienicwood mattress
28
mattress toppers
20
dust mite
20
house dust
16
test persons
16
bed dust
12
state health
12
mattress topper
12
mite antigen
12
antigen der
12

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!