The aim of this study was to examine the effects of physical, mental, social activity, and health concern on cognition in the elderly by means of the health concern and activity (HCA) model. Data were obtained from 3157 subjects aged 60 years and above. The subjects were divided into four groups according to the HCA model. Cognitive function was assessed by the Korean version of the mini-mental state examination (K-MMSE). A cross-sectional, factorial design was used in which the K-MMSE score was the dependent variable, with physical, mental, and social activity as one factor and health concern as the other. Analysis of covariance revealed significant differences in the K-MMSE score between all four groups after adjusting for age, sex, education, current smoking, and alcohol consumption for all subjects. The results suggest that having health concerns as well as physical, mental, or social activity is associated with cognitive function in the elderly.
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Biol Trace Elem Res
December 2024
Department of Microbiology, Faculty of Science, Bayelsa Medical University, Yenagoa, Bayelsa State, Nigeria.
This study assessed the safety of trace metal concentrations in locally produced nutritive food-drinks consumed in Yenagoa metropolis, Bayelsa State, Nigeria. Three different drink types (viz, tiger nut juice, a mixture of tiger nut and soya bean juice and soya bean juice) were purchased from various locations in Yenagoa metropolis, Bayelsa State, Nigeria, between January and February 2024. Thirty samples were analyzed for trace metals using atomic absorption spectrophotometry.
View Article and Find Full Text PDFDiscov Oncol
December 2024
Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Antibody-drug conjugates (ADCs) represent a novel class of targeted anti-tumor medications that utilize the covalent linkage between monoclonal antibodies and cytotoxic agents. This unique mechanism combines the cytotoxic potency of drugs with the targeting specificity conferred by antigen recognition. However, it is essential to recognize that many ADCs still face challenges related to off-target toxicity akin to cytotoxic payloads, as well as targeted toxicity and other potential life-threatening adverse effects, such as treatment-induced interstitial lung injury.
View Article and Find Full Text PDFCommunity Ment Health J
December 2024
School of Psychology, University of East London, London, UK.
The causal explanations voice-hearers have for their voice-hearing experiences may influence affective outcome and clinical decision making. Voice-hearers endorse a range of explanatory models, which do not consistently align with explanatory models held by healthcare professionals. Research has established that explanatory models for voice-hearing are dynamic rather than fixed, and are influenced by internal beliefs and motivations, culture, and contact with significant others.
View Article and Find Full Text PDFWorld J Urol
December 2024
Department of Urology, Baldwin Park Medical Center, Kaiser Permanente, 1011 Baldwin Park Blvd., Baldwin Park, CA, 91706, USA.
Purpose: To evaluate the accuracy, comprehensiveness, empathetic tone, and patient preference for AI and urologist responses to patient messages concerning common BPH questions across phases of care.
Methods: Cross-sectional study evaluating responses to 20 BPH-related questions generated by 2 AI chatbots and 4 urologists in a simulated clinical messaging environment without direct patient interaction. Accuracy, completeness, and empathetic tone of responses assessed by experts using Likert scales, and preferences and perceptions of authorship (chatbot vs.
Vet Sci
December 2024
Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.
Effective control of animal infectious diseases is crucial for maintaining robust livestock production systems worldwide. Porcine meat constitutes approximately 35-40% of global meat production with the largest producers being China and the European Union (EU). Emerging viral pathogens in swine, like porcine bocavirus (PBoV), have not garnered significant attention, leaving their pathogenic characteristics largely unexplored.
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