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The diagnostic dilemma of adrenal vascular tumors: analysis of 21 cases and systematic review of the literature.
Endocrine
January 2025
Anatomic Pathology - Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Purpose: Adrenal vascular tumors are mainly represented by adrenal cavernous hemangiomas (ACHs) and adrenal cystic lymphangiomas (ACLs). Their radiological features often overlap with malignant tumors, therefore ruling out malignancy becomes mandatory. We analyzed clinical, radiological, and histopathological data to identify specific characteristics of these tumors.
View Article and Find Full Text PDFDual-energy CT for differentiation of hypodense liver lesions in pancreatic adenocarcinoma.
Eur Radiol
December 2024
Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Objective: To assess the accuracy of CT spectral HU curve assessment of hypodense liver lesions.
Methods: In this retrospective HIPAA-compliant study (January 2016 through May 2023), patients with biopsy-proven pancreatic adenocarcinoma and a biopsied indeterminate liver lesion underwent a DECT abdominal CT scan. Spectral HU curves were provided for each hypodense liver lesion, and slopes were calculated.
Is the TriNetX Database a Good Tool for Investigation of Real-World Management of Von Hippel-Lindau?
J Kidney Cancer VHL
December 2024
Department of Urology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Article Synopsis
- The study explores the suitability of the TriNetX database for researching the real-world management of Von Hippel-Lindau (vHL), a rare hereditary disease characterized by various tumors.
- The researchers analyzed data from 1,232 patients diagnosed with vHL within the TriNetX database to identify the prevalence of several vHL-related conditions, finding that certain conditions like renal cell carcinoma and pheochromocytomas were more common than others.
- Despite the robust patient data available, the findings suggest that vHL and its associated conditions may be underdiagnosed within the TriNetX database, casting doubt on its effectiveness for comprehensive vHL studies compared to existing literature.
The challenges of hepatic epithelioid hemangioendothelioma: the diagnosis and current treatments of a problematic tumor.
Orphanet J Rare Dis
November 2024
Department of Hepatobiliary and Pancreatic Surgery, China-Japan Friendship Hospital, Beijing, China.
Article Synopsis
- Hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant vascular tumor with different types that affect prognosis and treatment plans, posing unique clinical challenges for diagnosis and therapy.
- The unclear causes of HEHE complicate its diagnosis, which often relies on tissue biopsy but encounters issues due to late identification and misdiagnosis, lacking specific treatment guidelines.
- Surgical options are the primary recommendation for better survival outcomes, but limited patient eligibility and donor organ shortages for liver transplants create obstacles; non-surgical treatments show promise but have limited research backing.
Epidermoid cyst in intrapancreatic accessory spleen (ECIPAS) is a rare benign condition that occasionally mimic malignant pancreatic neoplasms. We present a case of ECIPAS in a 53-year-old asymptomatic male, initially discovered incidentally during imaging for a suspected hepatic hemangioma. The lesion, located in the pancreatic tail, demonstrated characteristic imaging features on contrast-enhanced computed tomography and superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging (MRI), including a cystic component with peripheral solid tissue exhibiting splenic enhancement patterns.
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