The purposes of this survey were to determine the attitudes and the extent of anxiety of pregnant and lactating women about drug use, and to research priority issues for pharmacists' intervention. Postpartum lactating women and mothers with children in a Growing Care Unit (GCU) in hospitals certified as Baby Friendly Hospital (BFH) were surveyed. The questions included the images the respondents had of drugs before pregnancy, the extent of anxiety about drug use, and ways to relieve it. The highest number of respondents (49.1%) did not want to use drugs often before pregnancy, but said "physician-prescribed drugs are fine". 24.5% had no negative images, and they "take drugs when necessary without worrying". An additional 14.2% did not like drugs, and "avoid them whenever possible", followed by 9.4% who did not want to use drugs, but were willing to take health food and other over-the-counter items. The respondents reported that the extent of anxiety about drug use was 79.3% during pregnancy, which was higher than 71.7% during lactation. It was not influenced by birth experience and age. "The images of drugs before pregnancy" and "the extent to which the anxiety was relieved during pregnancy" were extracted as factors related to the extent of anxiety, verifying that negative images of drugs and low degrees of relief from anxiety raise the anxiety of pregnant women. The above shows that pharmacists need to understand the anxiety of pregnant and lactating women about drug use, and the images they had of drugs before pregnancy, thereby they are expected to work actively to determine and relieve the anxiety.
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http://dx.doi.org/10.1248/yakushi.130.1381 | DOI Listing |
Sci Data
January 2025
University of Bergen, Department of Clinical Medicine, Bergen, 5009, Norway.
Mental health is vital to human well-being, and prevention strategies to address mental illness have a significant impact on the burden of disease and quality of life. With the recent developments in body-worn sensors, it is now possible to continuously collect data that can be used to gain insights into mental health states. This has the potential to optimize psychiatric assessment, thereby improving patient experiences and quality of life.
View Article and Find Full Text PDFBrain Behav
January 2025
Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Purpose: Essential tremor (ET) is a prevalent movement disorder, yet current therapeutic options remain limited. Emerging evidence implicates leucine-rich repeat and immunoglobulin-like domain-containing protein (Lingo-1) and neuroinflammation in the pathophysiology of ET. This study aimed to investigate whether agmatine, a biogenic amine neuromodulator attenuates tremors and modulates the expression of Lingo-1 and proinflammatory markers in a rodent model of ET.
View Article and Find Full Text PDFNeuroimage
January 2025
School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, China. Electronic address:
Background: Although epigenomic and environment interactions (Epigenome × Environment; Epi × E) might constitute a novel mechanism underlying reward processing direct evidence is still scarce. We conducted the first longitudinal study to investigate the extent to which DNA methylation of a stress-related gene-NR3C1-interacts with childhood maltreatment in association with young adult reward responsiveness (RR) and the downstream risk of depressive (anhedonia dimension in particular) and anxiety symptoms.
Method: A total of 192 Chinese university students aged 18∼25 (M = 21.
PLoS One
January 2025
Department of Otolaryngology-Head & Neck Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Background: Despite several studies having correlated Alzheimer's disease with mental health conditions, the extent to which they have been incorporated into Alzheimer's disease clinical trials remains unclear.
Objective: This study aimed to assess the temporal trends in mental health-related terminology in Alzheimer's disease clinical trials as a proxy measure of research interest. Additionally, it sought to determine the effect of the COVID-19 pandemic on the frequency of these terms through pre-pandemic and post-pandemic trend assessment.
Behav Sci (Basel)
December 2024
Department of Military Medical Psychology, Air Force Medical University, Xi'an 710032, China.
In uncertain situations, individuals seek to maximize rewards while managing risks. Yet, the effects of acute stress and anxiety on decision-making in ambiguous and risky contexts are unclear. This study aims to contribute to the exploration of how acute stress influences sensitivity to immediate vs.
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