Background: a reliable assessment of mandibular invasion is crucial for treatment planning to obtain both radical tumor resection and good functional results.
Purpose: to retrospectively compare the diagnostic value of three different imaging methods - computed tomography (CT), magnetic resonance (MR) imaging, (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT - and their combined use for detection of mandibular invasion by squamous cell carcinoma (SCC) of the oral cavity.
Material And Methods: forty-six patients (39 men and 7 women; mean age, 59.4 years) suspected of having mandibular invasion by SCC of the oral cavity underwent CT, MR, and PET/CT within 2 weeks before surgery. First, each study was reviewed separately for the presence of mandibular invasion by tumors. Then, the value of combined images was assessed based on a confidence rating score for each modality assigned by observers. These results were verified with histopathologic findings.
Results: HIstopathologic examination revealed mandibular invasion in 12 of 46 SCCs. The sensitivity, specificity, and accuracy were 41.7%, 100%, and 84.8% for CT; 58.3%, 97.1%, and 87.0% for MR; and 58.3%, 97.1%, and 87.0% for PET/CT, respectively. The comparison of these modalities showed no statistically significant difference among them (P > 0.05). The combination of CT, MR, and PET/CT improved sensitivity (83.3%), without loss of specificity (100%) and accuracy (95.7%), although the difference failed to reach statistical significance (P > 0.05).
Conclusion: the combined analysis of CT, MR, and PET/CT can improve sensitivity in the detection of mandibular invasion by SCC of the oral cavity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/02841851.2010.520027 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Postoperative high-dose-rate brachytherapy alone in stage T1-3N0M0 oral cancer with negative prognostic factors: A retrospective study.
Brachytherapy
December 2024
Department of Oncology and Radiotherapy, University Hospital and Medical Faculty Hradec Kralove Hradec Kralove, Czech Republic.
Purpose: To evaluate treatment outcomes and toxicity in patients with stage T1-3N0M0 oral cancer treated with surgery followed by high-dose-rate brachytherapy (HDR-BT).
Methods And Materials: Retrospective study of 50 patients with stage T1-T3N0 tongue and floor-of-mouth cancer who underwent tumour excision (+ elective neck dissection) followed by postoperative HDR-BT due to the presence of negative prognostic factors (close or positive resection margins, lymphovascular and/or perineural invasion, deep invasion). The plastic tube technique (dose: 18 x 3 Gy b.
Invasive cervical root resorption in a cancer patient: A rare case report with 2 years of follow-up and literature review.
Spec Care Dentist
December 2024
Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Introduction: Cases involving invasive cervical root resorption (ICRR) in oncological patients are rare, in addition, follow-up of these patients has not yet been reported in the literature.
Objective: This study aims to present a literature review and report a case of denosumab as a possible cause of ICRR in a patient with breast cancer with 2 years of follow-up.
Case Report: A 39-year-old female with a history of luminal breast cancer was treated with denosumab semiannually for osteopenia with discontinuation 1 year ago.
Efficacy of Laser Activated versus Sonic Activated Irrigation for Debris Removal in Conservatively Instrumented Root Canals.
J Endod
December 2024
Department of Endodontics, Texas A&M College of Dentistry, Dallas, Texas. Electronic address:
Introduction: To compare the efficacy of laser activated and sonic activated irrigation on the removal of debris in mesial root canal systems of mandibular molars using micro-computed tomographic analysis.
Methods: Forty-eight mesial roots of extracted mandibular molars with isthmus were selected and randomly allocated into 2 groups: Sonic Group and Laser Group. The root canals were minimally instrumented to a maximum apical file size of 20/06v (DCTaper, SSWhite, NJ).
Peripheral Ameloblastoma Resembling an Exophytic Gingival Lesion: A Report of a Rare Case.
Cureus
November 2024
Oral and Maxillofacial Surgery, Burdwan Dental College and Hospital, Burdwan, IND.
Peripheral ameloblastoma is a rare, benign, slow-growing odontogenic neoplasm prevalent in the mandible. It originates from the odontogenic epithelium and its remnants, and its histological characteristics are identical to those of intraosseous ameloblastoma. It is less aggressive and invasive than its intraosseous variety, with a low recurrence rate.
View Article and Find Full Text PDFDiagnostic Accuracy of Dynamic High-Resolution Ultrasonography in Assessing Anterior Disc Displacement in Temporomandibular Joint Disorders: A Prospective Observational Study.
Healthcare (Basel)
November 2024
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral Medical Imaging, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
The objective of this study was to assess the diagnostic efficacy of dynamic high-resolution ultrasonography (HRUS) in detecting anterior disc displacement with reduction (ADDWR) and anterior disc displacement without reduction (ADDWoR) in the temporomandibular joint (TMJ). A total of 144 TMJs was categorized into three groups according to the magnetic resonance imaging (MRI) findings, which served as the reference standard: the normal disc position (NDP) group, the ADDWR group, and the ADDWoR group. Static images of the TMJ in full opening and maximum intercuspal positions, along with dynamic sequences during jaw opening, were obtained utilizing a 14 MHz L-shaped linear array transducer.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!