AI Article Synopsis

Article Abstract

A 'living' controlled hydrogel formation method was first reported to create loose and compact in situ biodegradable hydrogels. The method executed under mild reaction conditions can conveniently tailor the hydrogel properties, and it has the potential to develop into a powerful tool for the design, synthesis, and self-assembly of novel tailor-made biomaterials and drug delivery systems.

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja106639cDOI Listing

Publication Analysis

Top Keywords

'living' controlled
8
biodegradable hydrogels
8
controlled situ
4
situ gelling
4
gelling systems
4
systems thiol-disulfide
4
thiol-disulfide exchange
4
exchange method
4
method tailor-made
4
tailor-made biodegradable
4

Similar Publications

Trees are complex and dynamic living structures, where structural stability is essential for survival and for public safety in urban environments. Tree forks, as structural junctions, are key to tree integrity but are prone to failure under stress. The specific mechanical contributions of their internal conical structures remain largely unexplored.

View Article and Find Full Text PDF

Background/objectives: With the improvement of living standards, alcoholic liver disease caused by long-term drinking has been a common multiple disease. Probiotic interventions may help mitigate liver damage caused by alcohol intake, but the mechanisms need more investigation.

Methods: This study involved 70 long-term alcohol drinkers (18-65 years old, alcohol consumption ≥20 g/day, lasting for more than one year) who were randomly assigned to either the BC99 group or the placebo group.

View Article and Find Full Text PDF

Background/objectives: This protocol describes a study to investigate the feasibility and preliminary efficacy of a novel Teaching Kitchen Multisite Trial (TK-MT) for adults with cardiometabolic abnormalities. The TK-MT protocol describes a hybrid lifestyle intervention combining in-person and virtual instruction in culinary skills, nutrition education, movement, and mindfulness with community support and behavior change strategies. This 18-month-long randomized controlled trial aims to evaluate the feasibility of implementing a 12-month, 24 class program, assess preliminary study efficacy, and identify barriers and facilitators to implementation.

View Article and Find Full Text PDF

Mechanical Properties and Decomposition Behavior of Compression Moldable Poly(Malic Acid)/-Tricalcium Phosphate Hybrid Materials.

Polymers (Basel)

January 2025

Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, 1-8-14 Kandasurugadai, Chiyoda-ku, Tokyo 101-8308, Japan.

Calcified tissues in living organisms, such as bone, dentin, and enamel, often require surgical intervention for treatment. However, advances in regenerative medicine have increased the demand for materials to assist in regenerating these tissues. Among the various forms of calcium phosphate (CaP), tricalcium phosphate (TCP)-particularly its α-TCP form-stands out due to its high solubility and efficient calcium release, making it a promising candidate for bone regeneration applications.

View Article and Find Full Text PDF

Efficacy of Intraoperative Paracetamol and Nefopam Infusions in Addition to Transversus Abdominis Plane Block in Kidney Transplant Recipients.

Medicina (Kaunas)

January 2025

Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

: Kidney transplantation (KT) is an important treatment modality for renal failure. However, moderate-to-severe pain often occurs in KT recipients. Multimodal analgesia using combined analgesic measures has been recommended to enhance postoperative recovery.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!