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A concise and convergent synthesis of PA-824. | LitMetric
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A concise and convergent synthesis of PA-824.

Maurice A Marsini Paul J Reider Erik J Sorensen

J Org Chem

Department of Chemistry, Frick Chemical Laboratory, Princeton University, Princeton, New Jersey 08544, United States.

Published: November 2010

An efficient four-step synthesis of PA-824, a promising antituberculosis drug candidate, has been developed. This concise approach offers significant improvements over the synthetic route currently used for large-scale production.

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 Source
http://dx.doi.org/10.1021/jo1015807DOI Listing

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