The combination of simple Electrochemical Micro-Paper-based Analytical Devices (EµPADs) with commercially available glucometers allows rapid, quantitative electrochemical analysis of a number of compounds relevant to human health (e.g., glucose, cholesterol, lactate, and alcohol) in blood or urine.
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http://dx.doi.org/10.1039/c0lc00237b | DOI Listing |
Lab Chip
January 2025
School of Advanced Technology, Xi'an Jiaotong-Liverpool University, Suzhou, 215000, China.
Alzheimer's disease (AD) is the leading cause of dementia worldwide, and the development of early screening methods can address its significant health and social consequences. In this paper, we present a rotary-valve assisted paper-based immunoassay device (RAPID) for early screening of AD, featuring a highly integrated on-chip rotary micro-valve that enables fully automated and efficient detection of the AD biomarker (amyloid beta 42, Aβ42) in artificial plasma. The microfluidic paper-based analytical device (μPAD) of the RAPID pre-stores the required assay reagents on a μPAD and automatically controls the liquid flow through a single valve.
View Article and Find Full Text PDFTalanta
January 2025
State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University, Lanzhou, Gansu, 730000, People's Republic of China. Electronic address:
Mercury (II) ions (Hg) are a significant source of heavy metal contamination in groundwater, posing a serious threat to human health and the environment. Therefore, there is an urgent need for the development of a new detection technique with high sensitivity for monitoring Hg in contaminated groundwater. Here, we developed a signal amplifying MOF-based probe (NXS@ZIF-8) for on-site and ultrasensitive dual-channel portable detection of Hg in groundwater.
View Article and Find Full Text PDFSoc Sci Med
January 2025
Department of Social Anthropology, School of Social and Political Science, The University of Edinburgh, Scotland, UK. Electronic address:
Integrated Management of Childhood Illness (IMCI) is a strategy that aims to standardise clinical assessment and treatment of sick children. In this article, we examine the aspirations and unfolding of introducing a revised IMCI strategy in Bangladesh. We carried out ethnographic fieldwork among project implementors and in IMCI health service delivery settings in Kushtia district, including 36 semi-structured interviews with policymakers, programmers and IMCI service providers.
View Article and Find Full Text PDFAnal Chem
January 2025
Department of Applied Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
The integration of barcode technology with smartphones on paper-based analytical devices (PADs) presents a promising approach to bridging manual detection with digital interpretation and data storage. However, previous studies of 1D barcode approaches have been limited to providing only a "yes/no" response for analyte detection. Herein, a method of using barcode readout for semiquantitative signal detection on PADs has been achieved through the integration of barcode technology with a distance-based measurement concept on PADs.
View Article and Find Full Text PDFBMC Palliat Care
January 2025
Department of Nursing and Midwifery, Faculty of Medicine and Health Sciences, An Najah National University, Nablus, Palestine.
Background: Palliative care aims to improve quality of life for patients with end-stage illnesses by addressing physical, psychological, social and spiritual needs. Early referral to palliative care improves patient outcomes, quality of life and overall survival in a variety type of cancers. This study aimed to assess knowledge, attitudes and perceived benefits of early integration of palliative care among oncology nursing.
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