AI Article Synopsis
- Telomeres help prevent cancer by limiting cell division, but short telomeres can also lead to chromosome instability, contributing to cancer development.!
- Certain diseases show a link between short telomeres and increased cancer risk, but using telomere length as a reliable cancer predictor has largely failed.!
- Scientists are exploring the connection between telomeres, telomerase, and cancer to create new treatment strategies in cancer therapy.!
Article Abstract
Telomeres are a double-edged sword when it comes to cancer. On one hand, telomeres limit the cells' ability to divide and thereby restrict the uninhibited growth seen in cancer. On the other hand, short telomeres can initiate the chromosome instability that characterizes cancer. Diseases with the combination of short telomeres and high cancer risk are seen, but until now the use of telomeres as predictors of cancer has, in general, been unsuccessful. Telomeres and telomerase play an important role in further cancer development. Researchers are trying to exploit this in the development of new cancer therapies.
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