In this study, surface-enhanced Raman scattering (SERS) in combination with a heat-induced sensing technique has been applied for investigating molecular orientations of glutathione molecules adsorbed on silver colloidal nanoparticles under different chemical environments, which has enabled us to further study how glutathione molecules are adsorbed on the silver surfaces. Factors that may affect the configurations of glutathione molecules adsorbed on the silver nanocolloids have been investigated. By observing the relative enhancement factors of SERS bands due to individual functional groups contributed from different terminals, the affinity between the different functional groups of glutathione and the silver surfaces under different conditions has been sorted and the orientations of glutathione molecules adsorbed on the silver surfaces have been investigated.
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http://dx.doi.org/10.1366/000370210792973523 | DOI Listing |
Metab Brain Dis
January 2025
Neurobiology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
Aluminium is a common metallic toxicant that easily penetrates the brain and exerts severe pathological effects e.g., oxidative stress, inflammation and neurodegeneration.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
CSIR-National Botanical Research Institute (CSIR-NBRI), Rana Pratap Marg, Lucknow 226001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), P.O. CIMAP, Near Kukrail Picnic Spot, Lucknow 226 015, India. Electronic address:
Heavy metalloid stress such as arsenic (As) toxicity and nutrient imbalance constitute a significant threat to plant productivity and development. Plants produce sulfur (S)-rich molecules like glutathione (GSH) to detoxify arsenic, but sulfur deficiency worsens its impact. Previous research identified Arabidopsis thaliana ecotypes Koz2-2 (tolerant) and Ri-0 (sensitive) under low-sulfur (LS) and As(III) stress.
View Article and Find Full Text PDFPlant Physiol Biochem
January 2025
College of Horticulture and Landscape Architecture, Southwest University, Beibei, Chongqing, 400715, China. Electronic address:
The plant UDP-glycosyltransferases (UGTs) regulate several metabolic processes during root growth and development by conjugating sugar moieties to various small molecules. RsUGT71B5 is a novel UDP-glycosyltransferase in Raphanus sativus L., but its biological function is not well established.
View Article and Find Full Text PDFNat Commun
January 2025
National Institute for Physiological Sciences, National Institutes of Natural Sciences (NINS), Okazaki, Japan.
The presence of redox-active molecules containing catenated sulfur atoms (supersulfides) in living organisms has led to a review of the concepts of redox biology and its translational strategy. Glutathione (GSH) is the body's primary detoxifier and antioxidant, and its oxidized form (GSSG) has been considered as a marker of oxidative status. However, we report that GSSG, but not reduced GSH, prevents ischemic supersulfide catabolism-associated heart failure in male mice by electrophilic modification of dynamin-related protein (Drp1).
View Article and Find Full Text PDFEur J Med Chem
December 2024
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, PR China. Electronic address:
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