Falls are a major problem in older adults worldwide with an estimated 30% of elderly adults over 65 years of age falling each year. The direct and indirect societal costs associated with falls are enormous. A system that could provide an accurate automated assessment of falls risk prior to falling would allow timely intervention and ease the burden on overstretched healthcare systems worldwide. An objective method for assessing falls risk using body-worn kinematic sensors is reported. The gait and balance of 349 community-dwelling elderly adults was assessed using body-worn sensors while each patient performed the "timed up and go" (TUG) test. Patients were also evaluated using the Berg balance scale (BBS). Of the 44 reported parameters derived from body-worn kinematic sensors, 29 provided significant discrimination between patients with a history of falls and those without. Cross-validated estimates of retrospective falls prediction performance using logistic regression models yielded a mean sensitivity of 77.3% and a mean specificity of 75.9%. This compares favorably to the cross-validated performance of logistic regression models based on the time taken to complete the TUG test (manually timed TUG) and the Berg balance score. These models yielded mean sensitivities of 58.0% and 57.8%, respectively, and mean specificities of 64.8% and 64.2%, respectively. Results suggest that this method offers an improvement over two standard falls risk assessments (TUG and BBS) and may have potential for use in supervised assessment of falls risk as part of a longitudinal monitoring protocol.
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http://dx.doi.org/10.1109/TBME.2010.2083659 | DOI Listing |
JACC Adv
December 2024
Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Background: Frailty is a known determinant of poor clinical outcomes in heart failure with preserved ejection fraction (HFpEF). However, prevalence estimates and effect sizes vary in part due to multiple tools available to measure frailty.
Objectives: This study aimed to compare the prevalence and prognostic value of six commonly used frailty assessments in adults with HFpEF.
BMC Med Res Methodol
December 2024
Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Background: Graft loss is a major health concern for kidney transplant (KTx) recipients. It is of clinical interest to develop a prognostic model for both graft function, quantified by estimated glomerular filtration rate (eGFR), and the risk of graft failure. Additionally, the model should be dynamic in the sense that it adapts to accumulating longitudinal information, including time-varying at-risk population, predictor-outcome association, and clinical history.
View Article and Find Full Text PDFBMC Musculoskelet Disord
December 2024
Department of Orthopaedics, School of Medicine, Zhongda Hospital, Southeast University, No. 87 Ding Jia Qiao, Nanjing, 210009, Jiangsu, China.
Background: Osteosarcopenia is a geriatric syndrome associated with an increased risk of frailty, falls, fractures, disability, and death. Calf circumference (CC) has been used as a simple and practical skeletal muscle marker to diagnose sarcopenia. This study aimed to explore the relationship of calf circumference and osteoporosis (OP) and hip fractures (HF) in middle-aged and older adults.
View Article and Find Full Text PDFCardiol Res Pract
December 2024
Department of Family Medicine, Medical University of Białystok, Podlaskie Voivodeship, 15-054 Białystok, Poland.
Arterial stiffness, as determined by pulse wave velocity (PWV), is a recognized marker of cardiovascular risk. Noninvasive technologies have enabled easier and more accessible assessments of PWV. The current gold standard for measuring carotid-femoral PWV (cfPWV)-a reliable indicator of arterial stiffness-utilizes applanation tonometry devices, as recommended by the Artery Society Guidelines.
View Article and Find Full Text PDFEur J Med Res
December 2024
Department of Neurology, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc, Czech Republic.
Background: Idiopathic normal pressure hydrocephalus (iNPH) is a progressive disease characterized by disproportionate ventricular enlargement at brain imaging with gait disturbance and an increased risk of falling. Gait assessment is a key feature in the diagnosis of iNPH and characterization of post-surgical outcomes.
Research Question: How do gait parameters change 24 h after CSF tap test (CSFTT) and after ventriculoperitoneal shunt surgery?
Methods: The PRISMA guidelines were used to perform the systematic review.
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