Objectives: Evaluation of the performance of a modified Enzyme Multiplied Immunoassay Technique for therapeutic drug monitoring of plasma free mycophenolic acid (fMPA) concentrations.
Design And Methods: A fMPA assay was developed on a Viva-E analyzer. A study of prior ultrafiltration conditions and analytical validation of the EMIT assay were performed.
Results: The method was reliable and reproducible.
Conclusions: fMPA levels can be monitored using this EMIT assay with the advantage of being an automated method.
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| http://dx.doi.org/10.1016/j.clinbiochem.2010.09.025 | DOI Listing |
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