The phenomenon of a "local punch" of tissues in the zone of nano- or picosecond impulses of neodymium: YAG-laser radiation focusing allows to increase energy in the pulse by one order as compared with traditionally used energy. At this, in order to achieve the initial effect it becomes possible to reduce the number of shots by two orders and thus to increase the spot of radiation. The summary energy of action absorbed in the eye remains the same and that's why the number of complications doesn't increase. The widening of possibilities to choose a laser source for micro- and macroperforations allows, when prescribing the treatment, to more reliably consider clinical peculiarities in each concrete case.
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Cir Cir
January 2025
Department of Anesthesiology and Critical Care, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Objective: The agitation that can occur in patients undergoing vitreoretinal surgery on awakening from general anesthesia is a serious post-operative problem. In our study, we aimed to compare the effects of different anesthesia methods on emergence agitation in patients undergoing vitreoretinal surgery.
Method: Patients undergoing vitreoretinal surgery were divided into two groups: Total intravenous anesthesia (Group T) and inhalation anesthesia (Group D) according to the maintenance of anesthesia applied by consulting the records.
Urogynecology (Phila)
December 2024
From the Albany Medical Center Department of Obstetrics and Gynecology, Division of Urogynecology, Albany, NY.
Importance: A vaginal pessary is a highly effective treatment for patients with pelvic organ prolapse (POP). Patient views of pessaries and how their beliefs affect whether they choose pessary treatment is unknown.
Objective: Our objective of this study was to describe the knowledge, understanding, and patient concerns regarding pessary use for POP management.
Melanoma Res
February 2025
Department of Public Health, College of Medicine, Taipei Medical University.
Melanoma is an aggressive tumor that is challenging to treat. Talimogene laherparepvec (T-VEC), the first oncolytic virus treatment approved by the US Food and Drug Administration to treat unresectable melanoma, was recently used in recurrent tumors after initial surgery. Our network meta-analysis aimed to compare T-VEC treatment of metastatic melanoma with treatment of granulocyte-macrophage colony-stimulating factor (GM-CSF) and control group.
View Article and Find Full Text PDFWounds
December 2024
Smith+Nephew, Watford, Hertfordshire, UK.
Background: Achievement of moisture balance can be a critical factor affecting time to closure of nonhealing wounds, and dry wounds can take much longer to heal than those with high exudate levels. Whether the goal of management is to donate moisture to the wound or control excessive fluid until the cause has been identified and addressed, choice of dressing and other wound management products can affect nursing resources, clinical outcomes, concordance, and quality of life for the patient.
Case Reports: The cases discussed illustrate differences in management approaches for dry and wet wounds and show how clinician support tools (eg, tissue type, infection/inflammation, moisture imbalance, epithelial edge advancement [TIME] clinical decision support tool) can facilitate treatment decisions.
Neural Comput
January 2025
Intelligent Systems Research Centre, School of Computing, Engineering and Intelligent Systems, Ulster University, BT48 7JL Derry-Londonderry, Northern Ireland, U.K.
Decision formation in perceptual decision making involves sensory evidence accumulation instantiated by the temporal integration of an internal decision variable toward some decision criterion or threshold, as described by sequential sampling theoretical models. The decision variable can be represented in the form of experimentally observable neural activities. Hence, elucidating the appropriate theoretical model becomes crucial to understanding the mechanisms underlying perceptual decision formation.
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