Cultured murine epidermal keratinocyte allografts, depleted of MHC class II positive Langerhans cells, are not rejected by normal adult mice. This study investigates the survival of rat keratinocyte allografts depleted of MHC class II positive cells. Our results show that rat keratinocyte allografts are rejected rapidly in the absence of donor-derived, Langerhans cells. These allografts are, however, induced to express class II molecules in vivo, independently of graft rejection.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
keratinocyte allografts
16
epidermal keratinocyte
8
allografts depleted
8
depleted mhc
8
mhc class
8
class positive
8
langerhans cells
8
rat keratinocyte
8
allografts
5
rejection mhc
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!