Postmortem in situ micro-CT evaluation of coronary stent fracture.

Catheter Cardiovasc Interv

Cardiology Section, Dartmouth Medical School/Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756-0001, USA.

Published: October 2010

AI Article Synopsis

  • The study highlights the potential link between coronary stent fractures and complications like restenosis and thrombosis.
  • A case involving a 43-year-old man revealed significant fractures in a sirolimus-eluting stent (SES) after he received a paclitaxel-eluting stent (PES).
  • The use of microcomputed tomography (micro-CT) demonstrated detailed, nondestructive imaging, showing that the most severe stent fractures coincided with areas of significant luminal narrowing.

Article Abstract

Unlabelled: Coronary stent fracture has been postulated as an important mechanism for in-stent restenosis and late-stent thrombosis. We have developed a nondestructive microcomputed tomography (micro-CT) technique to image en bloc stented arterial segments.

Case Report: A 43-year-old man died of sepsis 5 months following placement of a paclitaxel-eluting stent (PES) in the left circumflex coronary artery to treat in-stent restenosis of a sirolimus-eluting stent (SES). Micro-CT three-dimensional images of the overlapping stents were notable for numerous connecting element fractures along the length of the SES. No fractures were observed in the PES. The greatest area of luminal narrowing is related to the region of most extensive stent fracture. Micro-CT of en bloc specimens provides high resolution (16 μm), three-dimensional images allowing for visualization of the stented arterial segment in a nondestructive manner.

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http://dx.doi.org/10.1002/ccd.22498DOI Listing

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