Advances in experimental medicine and technological innovation during the past century have brought tremendous progress in modern medicine and generated an ever-increasing amount of data from bench and bedside. The desire to extend scientific knowledge motivates effective data integration. Technological innovation makes this possible, which in turn accelerates the advancement in science. This mutually beneficial interaction is illustrated by the development of an expanded mechanism-based model for understanding a novel mechanism, sodium-glucose cotransporter-2 SGLT2 inhibition for potential treatment of type 2 diabetes mellitus.
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A new phase of China-ASEAN health cooperation: the China-ASEAN Beijing Declaration on Cooperation in Innovation of Health Products and Technologies.
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Department of Global Health, School of Public Health, Peking University, Beijing, China.
Utilizing innovative methods to advance the research and development (R&D) of health products and enhance their accessibility has become crucial to achieving universal health coverage, addressing public health emergencies, and promoting population health and wellbeing. However, structural contradictions do exist in the supply and demand of health products in the Association of Southeast Asian Nations (ASEAN). With the joint support of the Ministry of Science and Technology of China, the Ministry of Education, and the China-ASEAN Center, Peking University established the China-ASEAN Science and Technology Cooperation Center for Public Health in April 2023.
View Article and Find Full Text PDFAssociation of whole grain food consumption with lung cancer risk: a prospective cohort study.
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Radiation Oncology Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.
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Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
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View Article and Find Full Text PDFCatechol redox maintenance in mussel adhesion.
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Catechol-functionalized proteins in mussel holdfasts are essential for underwater adhesion and cohesion and have inspired countless synthetic polymeric materials and devices. However, as catechols are prone to oxidation, long-term performance and stability of these inventions awaits effective antioxidation strategies. In mussels, catechol-mediated interactions are stabilized by 'built-in' homeostatic redox reservoirs that restore catechols oxidized to quinones.
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