Enantioselective rhodium-catalyzed addition of arylboronic acids to alkenylheteroarenes.

J Am Chem Soc

School of Chemistry, University of Edinburgh, Joseph Black Building, The King's Buildings, West Mains Road, Edinburgh, EH9 3JJ, United Kingdom.

Published: October 2010

AI Article Synopsis

  • A newly developed chiral diene ligand in a rhodium complex enables efficient conjugate additions.
  • This process involves alkenes that are activated by both π-deficient and π-excessive heteroarenes.
  • The result is highly enantioselective reactions with different arylboronic acids.

Article Abstract

In the presence of a rhodium complex containing a newly developed chiral diene ligand, alkenes activated by a range of π-deficient or π-excessive heteroarenes engage in highly enantioselective conjugate additions with various arylboronic acids.

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Source
http://dx.doi.org/10.1021/ja106809pDOI Listing

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