By stimulating an enzyme, the sialyltransferase, Carbocisteine has a privileged place in mucomodifying therapeutics. It allows the substitution of pathologic secretions, congesting and aggressive, by physiologic restructured mucus. Tested with success in the E.N.T. catarrhal diseases, Rhinathiol interest is passed in review in each concerned pathologies. About interest of repairing mucociliary transport on the clinical symptomatology improvement.
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[A CASE OF STEVENS-JOHNSON SYNDROME SUSPECTED BY A COMMON COLD MEDICATION AS CAUSE].
Arerugi
June 2022
Department of Pediatrics, Kasugai Municipal Hospital.
We describe here the case of a 7-year-old male patient with Stevens-Johnson syndrome (SJS), which was suspected to be caused by treatment with tipepidine hibenzate (Asverin). The day after taking tipepidine hibenzate and L-carbocysteine (Carbocysteine DS) for relief of a cold, he began presenting with the following symptoms: fever above 38°C, wheezing, and decreased oxygen saturation. Two days later, mucous membrane rashes, such as erosions on the lips, eye mucosa, vulva, and blisters on the trunk appeared, and SJS was thus diagnosed.
View Article and Find Full Text PDFEfficacy and tolerability of a polysaccharide-resin-honey based cough syrup as compared to carbocysteine syrup for children with colds: a randomized, single-blinded, multicenter study.
World J Pediatr
February 2017
Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Background: Available pediatric treatments for acute cough are limited by lack of demonstrated efficacy. The objective of this trial is to compare the effects of a polysaccharide-resin-honey based cough syrup, and carbocysteine syrups on nocturnal and daytime cough associated with childhood upper respiratory tract infections (URIs).
Methods: Using a single-blind randomization design, the study recruited children from 4 general pediatric community clinics.
[A possible case of drug-induced pneumonia due to L-carbocisteine].
Nihon Kokyuki Gakkai Zasshi
August 2007
Division of Respiratory Medicine, Respirology and Stress Care Center, Kagoshima University Hospital.
A 70-year-old man presented with a deteriorating fever and productive cough after the administration of drugs including L-carbocisteine against the common cold. Since chest radiograph revealed pulmonary infiltrates in the right lower lung field, he was admitted to our hospital, then L-carbocisteine was continued and antibiotics started. However, his symptoms, laboratory findings, and hypoxia worsened.
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