Modular polyethylene liners offer versatility in total hip arthroplasty, but the locking mechanism may allow micromotion and backside wear. We evaluated the backside surface of 56 retrieved acetabular liners (mean 5.54 years in vivo, range 0.003-13.1 years) to determine whether damage correlated with liner age in vivo, patient factors associated with higher activity, and polyethylene quality. Half of the liners exhibited minimal damage, half exhibited no damage and none exhibited severe damage. Backside damage significantly correlated only to liner age in vivo. Ten of the 28 liners revised for osteolysis exhibited no backside damage, but the osteolytic cysts were peripheral and did not originate from screw holes. The results suggest that modular polyethylene liners in a porous titanium-coated shell with screw holes can be designed such that clinically significant backside wear is minimal.
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http://dx.doi.org/10.1016/j.arth.2010.07.012 | DOI Listing |
2'- -ribose methylation of the first transcribed base (adenine or A in SARS-CoV-2) of viral RNA mimics the host RNAs and subverts the innate immune response. How nsp16, with its obligate partner nsp10, assembles on the 5'-end of SARS-CoV-2 mRNA to methylate the A has not been fully understood. We present a ∼ 2.
View Article and Find Full Text PDFRSC Adv
December 2024
Department of Electrical and Electronic Engineering, University of Rajshahi Rajshahi 6205 Bangladesh
Molybdenum telluride (MoTe) shows great promise as a solar absorber material for photovoltaic (PV) cells owing to its wide absorption range, adjustable bandgap, and lack of dangling bonds at the surface. In this research, a basic device structure comprising Pt/MoTe/ZnO/ITO/Al was developed, and its potential was assessed using the SCAPS-1D software. The preliminary device exhibited a photovoltaic efficiency of 23.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
December 2024
Department of Physics, Harvard University, Cambridge, MA 02138.
A long-standing problem in the study of the under-hole-doped cuprates has been the description of the Fermi surfaces underlying the high magnetic field quantum oscillations, and their connection to the higher temperature pseudogap metal. Harrison and Sebastian [ , 226402 (2011)] proposed that the pseudogap "Fermi arcs" are reconstructed into an electron pocket by field-induced charge density wave order. But computations on such a model [Zhang and Mei, , 47008 (2016)] show an unobserved additional oscillation frequency from a Fermi surface arising from the backsides of the hole pockets completing the Fermi arcs.
View Article and Find Full Text PDFNanoscale
December 2024
South China Advanced Institute for Soft Matter Science and Technology, School of Emergent Soft Matter, South China University of Technology, Guangzhou 510640, China.
Phenolic and carbon aerogels have important applications for thermal insulation and ablative resistance materials in aerospace field. However, their antioxidant ability in long-term high-temperature aerobic environments faces serious challenges. To solve this problem, Zr/Si preceramic polymer hybridized phenolic resin (PR-ZS) aerogels were prepared a facile sol-gel method.
View Article and Find Full Text PDFWe consider avalanche photodiodes (APDs) functioning under near Geiger-mode operation for extremely weak light (single or several photons) detection, such as in LiDAR receivers. To meet such demands, APDs which simultaneously have a large active window size, moderate bandwidth (∼GHz), and high internal gain (responsivity), are highly desired. However, it is difficult to design APDs capable of meeting the afore-mentioned performance requirements due to the intrinsic limitations of the gain-bandwidth product (GBP).
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