We adapt an instance model of human memory, Minerva 2, to simulate retrospective revaluation. In the account, memory preserves the events of individual trials in separate traces. A probe presented to memory contacts all traces in parallel and causes each to become active. The information retrieved from memory is the sum of the activated traces. Learning is modelled as a process of cued-recall; encoding is modelled as a process of differential encoding of unexpected features in the probe (i.e., expectancy-encoding). The model captures three examples of retrospective revaluation: backward blocking, recovery from blocking, and backward conditioned inhibition. The work integrates an understanding of human memory and complex associative learning.
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http://dx.doi.org/10.1037/a0020886 | DOI Listing |
World J Gastroenterol
December 2024
Department of Surgery, Assab Military Hospital, Assab 291-1, Southern Red-sea Region, Eritrea.
The study by López-Gómez , reports a significantly low prevalence (4.5%) of () infection in esophageal cancer patients, contrasting sharply with the general population's infection rate. This finding challenges the established negative association between and gastric malignancies, suggesting a potential protective role of against esophageal carcinoma, particularly in the context of widespread proton pump inhibitor use.
View Article and Find Full Text PDFHistopathology
December 2024
Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, BC.
Aims: Mesonephric-like adenocarcinoma (MLA) of the endometrium is often a diagnostic challenge, due to its morphological resemblance to other more common Müllerian neoplasms. This study aimed to retrospectively identify overlooked MLA in a large endometrial carcinoma cohort, using a combination of immunohistochemistry (IHC), morphology and KRAS sequencing.
Methods And Results: IHC was conducted on 1094 endometrial carcinomas, identifying 16 potential MLA cases based on GATA3+ and/or TTF1+ and ER- staining patterns, which subsequently underwent detailed histological review, KRAS sequencing and ProMisE molecular classification.
BJUI Compass
September 2024
Department of Urology Austin Health Melbourne Victoria Australia.
Introduction And Objectives: Full blood examinations, often referred to as FBE, are commonly ordered postoperatively, despite limited utility in many of its markers in the acute phase. It is estimated that in the 2022-2023 financial year, the Australian healthcare system billed over $13 million for full blood examinations (FBEs) to Medicare. This study aims to assess the cost of using FBE following surgery.
View Article and Find Full Text PDFNeurol Sci
December 2024
Department of Neurosciences, Reproductive and Odonstomatological Sciences, University Federico II, Via Sergio Pansini, Naples, 5 - 80131, Italy.
Background And Aims: Charcot-Marie-Tooth (CMT) is a heterogeneous group of genetic neuropathies and is typically characterized by distal muscle weakness, sensory loss, pes cavus and areflexia. Herein we describe a case of CMT2CC presenting with proximal muscle weakness and equivocal electrophysiological features, that was misdiagnosed as chronic inflammatory demyelinating polyneuropathy (CIDP).
Case Report: A 30-year-old woman complained of proximal muscle weakness with difficulty climbing stairs.
PLoS One
August 2024
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Prediction errors have a prominent role in many forms of learning. For example, in reinforcement learning, agents learn by updating the association between states and outcomes as a function of the prediction error elicited by the event. One paradigm often used to study error-driven learning is blocking.
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