AI Article Synopsis
- The study aimed to evaluate the effectiveness of a compound traditional Chinese medicine (CTM) containing gallic acid, magnolol, and polysaccharide from Blettila striata against bacterial biofilms in infected root canals.
- Using confocal laser scanning microscopy (CLSM), researchers found that while both CTM and ZnO reduced biofilm thickness, CTM significantly decreased the viability of bacteria present in the biofilm.
- The results suggest that CTM is a promising disinfecting agent for root canal treatments, as supported by funding from the Bureau of Traditional Chinese Medicine of Shanghai Municipality.
Article Abstract
Purpose: To assess the efficacy of compound Chinese traditional medicine(CTM), which composed of gallic acid, magnolol and polysaccharide of Blettila striata, against the infected root canal bacterial biofilm.
Methods: Actinomyces viscosus (Av), Enterococcus faecalis (Ef), Fusobacterium nucleatum (Fn) were composed to form biofilm, then confocal laser scan microscope (CLSM) was used to observe and study the bacterial activity. SAS6.12 software package was used for statistical analysis.
Results: The biofilm thickness reduced after treatment by both CTM and ZnO (P>0.05),while there was a significant decrease of the percentage of vital bacterias after treatment by CTM (P<0.01).
Conclusions: The compound Chinese traditional medicine is effective on biofilm control, so that it would be an effective disinfecting drug for root canal sealers. Supported by Research Fund of Bureau of Traditional Chinese Medicine of Shanghai Municipality (Grant No.2008L008A).
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