The proteins encoded by MADS-box genes are a large number of transcription factors, which control plant growth and development by forming homo- or hetero-dimers. Here, we reviewed recent researches on the interactions of MADS-box transcription factors and manipulating fruit development and ripening, which will help us to understand the mechanism of MADS-box transcription factors and provide references for further investigating the functions of MADS-box genes on fruit development and ripening.
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