AI Article Synopsis
- The study by Cros et al. (2010) identifies specific subpopulations of monocytes in humans, namely CD14(+) inflammatory monocytes and CD14(dim)CD16(+) patrolling monocytes.
- These monocyte subpopulations have unique functional specializations, similar to those observed in murine models.
- This work helps to further understand the roles of different monocyte types in immune responses.
Article Abstract
Murine "inflammatory" and "patrolling" monocytes have specific functional specializations. In this issue of Immunity, Cros et al. (2010) characterize CD14(+) and CD14(dim)CD16(+) monocyte subpopulations as the human "inflammatory" and "patrolling" monocytes that, similarly to their mouse counterparts, are characterized by distinct functional properties.
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| http://dx.doi.org/10.1016/j.immuni.2010.09.007 | DOI Listing |
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