Sensitization to Cupressaceae pollen has become one of the most important causes of pollinosis in Western countries during winter and early spring. However, the characterization of the extracts, the allergens involved and the cross-reactivity with other pollen sources still remain poorly studied; in the case of Cupressus arizonica only two allergens have been described so far. A new allergen from C. arizonica pollen, Cup a 4, was cloned and expressed in Escherichia coli as an N-terminally His-tag recombinant protein that was characterized biochemically, immunologically and by circular dichroism spectroscopy. The new allergen has high sequence identity with Prickly Juniper allergen Jun o 4 and contains four EF-hand domains. The recombinant protein has structural similarities with other calcium binding allergens such as Ole e 3, Ole e 8 and Phl p 7. Cup a 4 is expressed in mature pollen grains and shares antigenic properties with the recombinant form. Sera from 9.6% C. arizonica allergic patients contain specific IgE antibodies against recombinant Cup a 4.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bbrc.2010.09.079 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Determination of the Suitable Biomonitors to be used in Monitoring the Change for Reducing the Concentration of V in Areas with High-Level of Air Pollution.
Bull Environ Contam Toxicol
November 2024
Faculty of Architecture, Department of City and Regional Planning, Ondokuz Mayis University, Samsun, ilkadim, 55020, Turkey.
In this study, Vanadium (V) concentrations were analyzed in five tree species (Pinus pinaster, Cupressus arizonica, Picea orientalis, Cedrus atlantica, and Pseudotsuga menziesii) from Duzce city (Turkey), a highly polluted area. The research compared V levels across species, organs, directions, and age groups over the past 40 years. Trees, which absorb nutrients from soil and air, were used as biomonitors.
View Article and Find Full Text PDFAccumulation of heavy metals in the leaves of different tree species and its association with the levels of atmospheric PM-bond heavy metals in Isfahan.
Int J Phytoremediation
October 2024
Department of Environmental Health Engineering, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
This study aimed to biomonitor air pollution by measuring heavy metals (HMs) accumulation levels in the leaves of common urban trees, , L., L. and in different regions of Isfahan.
View Article and Find Full Text PDFIdentification of proper species that can be used to monitor and decrease airborne Sb pollution.
Environ Sci Pollut Res Int
September 2024
Department of Environmental Engineering, Kastamonu University, 37150, Kastamonu, Turkey.
Heavy metal concentrations, which have increased continuously in the environment this century due to anthropogenic factors, severely threaten human and environmental health. Antimony (Sb) is one of the most toxic and harmful heavy metals in terms of human and environmental health. Therefore, the priority research subjects are monitoring the alteration of Sb pollution in the airborne and reducing pollution.
View Article and Find Full Text PDFAccumulation analysis and overall measurement to represent airborne toxic metals with passive tree bark biomonitoring technique in urban areas.
Environ Monit Assess
July 2024
Institute of Science, Düzce University, 81620, Düzce, Türkiye.
Authorities have long proved the utility of bioindicators in monitoring the state of environmental pollution. Some biological indicators can measure environmental pollutant levels, and many tree species have been tested for suitability for monitoring purposes. The differences in morphological characteristics in the trees have demonstrated the effects of human activities on different materials.
View Article and Find Full Text PDF: an emerging aeroallergen for East Mediterranean children.
Turk J Med Sci
May 2024
Department of Pediatric Allergy, Faculty of Medicine, Hacettepe University, Ankara, Turkiye.
Background/aim: is a tree native to the Mediterranean region. We aimed to investigate the frequency of sensitization/allergy to pollen, which is not native to Anatolia.
Materials And Methods: Patients aged 5-18 years who underwent respiratory allergy screening in Türkiye's largest referral center over a 1-year period were reviewed retrospectively for a diagnostic study of allergy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!