AI Article Synopsis
- GnRH agonists are shown to effectively preserve ovarian function during chemotherapy treatments.
- The initial surge of FSH after starting GnRH agonists poses a challenge for their use.
- Combining GnRH agonists with GnRH antagonists may help mitigate the FSH flare-up, making the treatment more effective.
Article Abstract
Increasing evidence supports GnRH agonists to be an effective treatment to preserve ovarian function during chemotherapy, but the initial flare-up of FSH during the first week after GnRH agonist application still limits its use. The combination of GnRH agonists with GnRH antagonists might solve this problem to some extent as the addition of GnRH antagonists at least significantly reduces the FSH flare-up.
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| http://dx.doi.org/10.1016/j.fertnstert.2010.08.053 | DOI Listing |
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