Objectives: Dexketoprofen trometamol is a water-soluble salt of the dextrorotatory enantiomer of the nonsteroidal anti-inflammatory drug ketoprofen. The aim of this study was to investigate the effect of intravenous dexketoprofen on postoperative pain.
Methods: This study was performed on 50 (ASA I-II) patients scheduled for abdominal hysterectomy. Fifty patients were randomized into two equal groups. Patients received saline solution (Group I) or 50 mg intravenous dexketoprofen (Group II) 1 hour (h) before surgery and 8-16 h after surgery. All patients received a standard anesthetic protocol. At the end of surgery, all patients received intravenous (IV) morphine via a PCA (patient- controlled analgesia) device. Pain scores were assessed at 2, 6, 12 and 24 h after surgery. Morphine consumption and adverse effects were noted during the first 24 h after the surgery. The pain scores were significantly lower in the dexketoprofen group compared with the control group (p<0.05).
Results: The cumulative morphine consumption was also lower in the dexketoprofen group than the control group (p<0.05). No significant difference was observed in adverse effects between the groups (p>0.05).
Conclusion: We conclude that the administration of IV dexketoprofen provided a significant analgesic benefit and decreased the morphine requirements in patients undergoing abdominal hysterectomy.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Outcomes of mobilization in the first hour following uniportal video-assisted thoracoscopic surgery for primary spontaneous pneumothorax.
Kardiochir Torakochirurgia Pol
March 2024
Department of Thoracic Surgery, Istinye University, Istanbul, Turkey.
Introduction: Although primary spontaneous pneumothorax is a common disease in young adults, each thoracic surgery department performs different procedures for its management.
Aim: The optimal time of postoperative mobilization is not yet standardized in lung surgery.
Material And Methods: This study included male patients with a primary spontaneous pneumothorax who underwent wedge resection of the upper lobe of the lungs via uniportal video-assisted thoracoscopic surgery.
Dexketoprofen versus Tenoxicam in Acute Severe Pain Due to Primary Dysmenorrhea.
J Coll Physicians Surg Pak
February 2024
Emergency Medicine Clinic, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye.
Objective: To evaluate the analgaesic efficacy of tenoxicam and dexketoprofen in patients admitted to the Emergency Medicine (EM) Clinic with severe acute pain due to primary dysmenorrhea (PD).
Study Design: Randomised-controlled trial. Place and Duration of the Study: Emergency Medicine Clinic, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye, from January to December 2022.
Pain management after total hip arthroplasty: comparative study of analgesic efficacy and tolerability between oral tramadol/dexketoprofen and injectable paracetamol + tramadol.
Hip Int
May 2024
Department of Orthopaedic Surgery and Musculoskeletal Trauma, University General Hospital of Larissa, School of Health Sciences, Faculty of Medicine, University of Thessaly, Larissa, Thessalia Sterea Ellada, Greece.
Background: Multimodal analgesia for total hip arthroplasty (THA) is increasingly employed to reduce early postoperative pain and promote fast patient discharge. The aim of this study was to compare the efficacy and tolerability of tramadol/dexketoprofen (TRAM/DKP, Group A) versus paracetamol + tramadol (PARA+TRAM, Group B) in patients undergoing THA using minimally invasive direct anterior approach (DAA).
Methods: A single-centre, randomised, single-blind, parallel, interventional study conducted in 323 patients undergoing primary THA with DAA was performed.
Comparison of the effects of one-level and bi-level pre-incisional erector spinae plane block on postoperative acute pain in video-assisted thoracoscopic surgery; a prospective, randomized, double-blind trial.
BMC Anesthesiol
August 2023
University of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Ankara, Turkey.
Article Synopsis
- This study compared the effectiveness of One-Level and Bi-Level erector spinae plane blocks for pain relief in patients undergoing video-assisted thoracic surgery.
- Conducted on 60 patients, it assessed pain levels using visual analog scale (VAS) scores at various postoperative intervals and monitored the use of additional analgesics and side effects.
- Results indicated that the Bi-Level ESPB provided better pain control for coughing, with significant differences in VAS scores at certain times, although both methods showed similar side effects and overall analgesic needs.
Placebo-controlled randomized double-blind comparison of the analgesic efficacy of lidocaine spray and etofenamate spray in pain control of rib fractures.
Ulus Travma Acil Cerrahi Derg
August 2023
Department of Emergency, Ankara Bilkent City Hospital, Ankara-Türkiye.
Background: As far as we could detect, we could not find any study in literature on the analgesic efficacy of spray forms of lidocaine and etofenamate in rib fractures. In this study, our aim is to empirically compare the analgesic efficacy of etofenamate spray, lidocaine 10% spray and placebo spray in the management of pain secondary to trauma secondary to isolated rib fractures.
Methods: The study was designed according to a single-center, prospective, randomized, placebo-controlled double-blind study model.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!