Fourteen patients (28 eyes) suffering from histologically confirmed temporal arteritis were examined with oculo-oscillodynamography (OODG) according to Ulrich and Ulrich as well as with orbital dynamography (ODG) according to Hager. These examinations were performed before and during prednisolone treatment. When ocular and orbital vessels are involved, temporal arteritis will result in a strong reduction of the ocular and orbital pulse blood volumes. Ocular perfusion pressures may also be reduced. In all 28 eyes of the 14 patients, OODG showed the ocular pulse blood volumes to be significantly reduced, while with ODG the ocular pulse blood volumes appeared to be within the normal range in 50% of the cases. Therefore, OODG is more reliable than ODG in the diagnosis of temporal arteritis. When performed during prednisolone treatment, OODG is a very sensitive indicator of successful or unsuccessful therapy. OODG permits an early detection of relapses and helps to avoid their sequelae. Since OODG can be repeated as often as desired and can be performed within a short time, it is very suitable for controlling the management of temporal arteritis.
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Intern Med
January 2025
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Japan.
We herein report the first case of dyspnea with hemidiaphragm elevation in a 68-year-old woman with active giant cell arteritis (GCA), including successful treatment. Contrast-enhanced computed tomography showed a reduced density of the left ophthalmic artery and the left superficial temporal artery with increased soft tissue compared to the other side, indicating that the GCA had flared up and suggesting that the hemidiaphragm elevation might be caused by vasculitis-associated ischemia of the right phrenic nerve. Hemidiaphragm paralysis due to vasculitis-associated ischemia in patients with GCA needs to be distinguished from local infection, tumors, and hepatomegaly, which are the major causes of hemidiaphragm elevation.
View Article and Find Full Text PDFClin Exp Rheumatol
January 2025
Division of Rheumatology, Mayo Clinic, Rochester, MN, USA.
Rheumatol Int
January 2025
Department of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Oberduerrbacher Strasse 6, 97080, Wuerzburg, Germany.
Background: Diagnosis of Giant Cell Arteritis (GCA) and Polymyalgia rheumatica (PMR) may be challenging as many patients present with non-specific symptoms. Superficial cranial arteries are predilection sites of inflammatory affection. Ultrasound is typically the diagnostic tool of first choice supplementary to clinical and laboratory examination.
View Article and Find Full Text PDFAutoimmun Rev
January 2025
Rheumatology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy; University of Modena and Reggio Emilia, Modena, Italy. Electronic address:
Giant cell arteritis (GCA), also known as temporal arteritis, is the most common form of vasculitis in the elderly. While initially described as involving the temporal arteries, GCA can also affect the aorta and its major branches. Despite the increased use of imaging modalities and the availability of temporal artery biopsy, diagnosing GCA remains challenging.
View Article and Find Full Text PDFMod Rheumatol
January 2025
Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Objectives: We applied the 2022 American College of Rheumatology (ACR)/European Alliance of Association for Rheumatology (EULAR) criteria to Korean patients previously diagnosed with giant cell arteritis (GCA) according to the 1990 ACR criteria and validated its clinical efficiency.
Methods: Nine patients with GCA were included in this study. The proportion of patients meeting each item of the 1990 ACR criteria and the 2022 ACR/EULAR criteria were assessed.
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